Challenges in Clinical Development of Mesenchymal Stromal/Stem Cells: Concise Review
Ilenia Mastrolia, et al., STEM CELLS Translational Medicine
This article highlights mesenchymal stromal/stem cell (MSC) strengths and overall weaknesses in order to contribute to the achievement of a better awareness of challenges related to MSC developments that should be taken into account in future MSC‐based therapeutics.
In Vitro Recapitulation of Developmental Transitions in Human Neural Stem Cells
Laura Ostermann, et al., STEM CELLS
This study describes the in vitro transition of neuroepithelial stem cells into radial glia-like stem cells in a human background. It also defines the developmental relationship between defined in vitro propagated human neural stem cell systems and provides a matrix for the comparability between pluripotent stem cell‐derived populations and their native counterparts in the brain.
Researchers employ a computational modeling technique to establish a relationship between exosomal miRNA and responses in a rat myocardial infarction model
A new study investigates the influence of HSV‐1 infection and Aβ accumulation on adult hippocampal neurogenesis by studying neural stem cells in vitro and in vivo
A new study demonstrates how the increased stiffness of the oligodendrocyte progenitor cell niche causes an age-related deterioration in stem cell functions