Featured Articles

Concise Review: A Safety Assessment of Adipose‐Derived Cell Therapy in Clinical Trials: A Systematic Review of Reported Adverse Events

This study reviewed the safety of adipose-derived cell therapy. Thromboembolic complications were noted following systemic administration of cells. The treatment has so far shown to be safe in the setting of previous cancer. Donor specific antibodies are produced when using allogeneic cells documenting that these cells are not immune privileged. The consequences of this needs further research. Future research should focus on higher quality of reporting of adverse events as the present literature is of low quality.



Concise Review: Mesenchymal Stem Cells in Neurodegenerative Diseases

Mesenchymal stem cells (MSCs) hold great potential as source for cell-based therapy for neurodegenerative diseases. In this review, we summarize recent progress using human MSC transplantation into rodent models of neurodegeneration. We examine the molecular mechanisms mediating disease amelioration through this approach and emphasize the potential of ex vivo manipulation for these cells before transplantation.

 

Journal Club Discussions

July 30, 2017

Researchers report on a successful cartilage repair trial using a simple strategy involving mesenchymal stem cell and patient-derived chondrocytes

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Article Scans

August 14, 2017
A new study identifies unbalanced skin stem cell division as a driving force behind psoriasis and report immune modulation as a potential treatment option
August 14, 2017
Research indicates that hypothalamic neurons innervate regional-specific SVZ-NSCs to produce neural cells in response to physiological status
August 7, 2017
Expansion and differentiation of cord blood in a bottle turning culture system may represent an effective large-scale means to produce human erythrocytes