Ottawa Health Research Institute
Ottawa ON, CANADA
Scientific Positions:
Senior Scientist and Director of the Regenerative Medicine Program and the Sprott Centre for Stem Cell Research, Ottawa Health Research Institute
Professor, Department of Medicine and Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa
Canada Research Chair in Molecular Genetics
Scientific Director, Stem Cell Network
Howard Hughes Medical Institute International Research Scholar
Dr Rudnicki's laboratory works to understand the molecular mechanisms that regulate the determination, proliferation, and differentiation of stem cells during embryonic development and during tissue regeneration. The lab has conducted extensive studies into both embryonic myogenesis and the function of stem cells in adult skeletal muscle. Towards this end, the lab employs molecular genetic and genomic approaches to determine the function and roles played by regulatory factors. They identified Pax7 as a transcription factor required for the specification of satellite cells, and identified Wnt signaling as playing an important role in the myogenic specification of adult stem cells. His research has been published in scientific journals that include Cell, Genes & Development, Nature Cell Biology and PLoS Biology.
His laboratory’s research interests include:
Stem Cells, Myogenesis, Embryogenesis, Molecular Biology, Transcriptional Regulation, Transcriptional Networks, Gene Expression, Cell Cycle, Cell Differentiation, Molecular Genetics
Rudnicki Lab Homepage
Canada Research Chair Website
Profile of Dr. Rudnicki at the HHMI
Website at The University of Ottawa
Link to The Stem Cell Network - Canada
Recent Publications (provided by The Ottawa Hospital Library Database)
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