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Clinical Trials: Cord Blood

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Body: Condition:   Inherited Metabolic Disorders (IMD)
Intervention:   Drug: MGTA-456
Sponsor:   Magenta Therapeutics, Inc.
Not yet recruiting
Body: Conditions:   Acute Biphenotypic Leukemia;   Acute Lymphoblastic Leukemia in Remission;   Acute Myeloid Leukemia in Remission;   Blasts Under 10 Percent of Bone Marrow Nucleated Cells;   Blasts Under 5 Percent of Bone Marrow Nucleated Cells;   Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Cytogenetic Abnormality;   High Risk Myelodysplastic Syndrome;   Myelodysplastic Syndrome With Excess Blasts;   Pancytopenia;   Refractory Anemia
Interventions:   Drug: Cyclophosphamide;   Drug: Fludarabine;   Other: Laboratory Biomarker Analysis;   Drug: Thiotepa;   Radiation: Total-Body Irradiation;   Biological: Umbilical Cord Blood-derived Hematopoietic CD34-positive Progenitor Cells;   Procedure: Umbilical Cord Blood Transplantation
Sponsors:   Fred Hutchinson Cancer Research Center;   National Cancer Institute (NCI);   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting
Body: Conditions:   Myelodysplastic Syndromes;   Leukemia, Myeloid, Acute;   Leukemia, Relapsed Adult Acute Myeloid;   Myelodysplastic Syndromes, Previously Treated
Interventions:   Drug: CPX-351;   Drug: Fludarabine;   Drug: Melphalan;   Drug: Rabbit Anti-Human T-Lymphocyte Globulin;   Biological: Haplo-Cord Stem Cell Transplantation
Sponsor:   Weill Medical College of Cornell University
Recruiting
Body: Condition:   Severe Bronchopulmonary Dysplasia
Interventions:   Biological: PNEUMOSTEM;   Other: Placebo
Sponsor:   Medipost Co Ltd.
Not yet recruiting
Body: Conditions:   Diabetes Mellitus, Type 1;   Diabetes Mellitus, Type 2
Intervention:   Combination Product: Stem Cell Educator therapy
Sponsors:   Tianhe Stem Cell Biotechnologies Inc.;   Chinese PLA General Hospital
Recruiting
Body: Condition:   Bronchopulmonary Dysplasia
Interventions:   Drug: transplantation of mesenchymal stem cell;   Drug: no transplantation of mesenchymal stem cell
Sponsors:   Daping Hospital and the Research Institute of Surgery of the Third Military Medical University;   Children's Hospital of Chongqing Medical University;   Chongqing Maternal and Child Health Hospital
Recruiting
Body: Conditions:   Severe Aplastic Anemia;   Hypo-Plastic MDS;   Myelodysplastic Syndrome (MDS)
Intervention:   Biological: CordIn(TM)
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified April 18, 2017
Body: Condition:   Alzheimer's Disease
Interventions:   Biological: human umbilical cord blood derived mesenchymal stem cells;   Other: Normal saline 2mL
Sponsor:   Medipost Co Ltd.
Recruiting - verified May 2017
Body: Condition:   Acute Graft Versus Host Disease
Intervention:   Biological: MSCTC-0010 Dose Escalation
Sponsor:   Joseph McGuirk
Not yet recruiting - verified May 2017
Body: Conditions:   Cerebral Palsy;   Child Development
Intervention:   Biological: allogeneic cord blood transplantation
Sponsor:   Bundang CHA Hospital
Recruiting - verified April 2017
Body: Condition:   Hematologic Disorders
Intervention:   Device: Miltenyi CliniMACS® CD34 Reagent System
Sponsor:   University of Colorado, Denver
Not yet recruiting - verified March 2017
Body: Condition:   Hematopoietic/Lymphoid Cancer
Interventions:   Drug: Busulfan;   Drug: Rituximab;   Drug: ATG;   Drug: Fludarabine;   Drug: Clofarabine;   Radiation: Total Body Irradiation;   Procedure: Cord Blood Transplant;   Drug: Mycofenolate mofetil;   Drug: Tacrolimus;   Drug: G-CSF;   Drug: Melphalan;   Drug: Cyclophosphamide;   Drug: Mesna
Sponsors:   M.D. Anderson Cancer Center;   Mesoblast, Inc.
Not yet recruiting - verified March 2017
Body: Condition:   Cerebral Palsy
Intervention:   Biological: Matched sibling donor cord blood cell infusion
Sponsors:   Murdoch Childrens Research Institute;   The Royal Children's Hospital Melbourne;   Children's Health Queensland;   Monash Health;   Sydney Children's Network;   Cerebral Palsy Alliance
Recruiting - verified March 2017
Body: Conditions:   Acute Myeloid Leukemia;   Acute Lymphocytic Leukemia;   Myelodysplastic Syndrome;   Non-hodgkin Lymphoma;   Chronic Lymphocytic Leukemia
Interventions:   Drug: Cyclophosphamide;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Other: Haploidentical Stem Cell Transplantation
Sponsor:   Loyola University
Recruiting - verified March 2017
Body: Conditions:   B-Lymphoid Malignancies;   Acute Lymphocytic Leukemia;   Chronic Lymphocytic Leukemia;   Non-hodgkin Lymphoma
Interventions:   Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Mesna;   Biological: iC9/CAR.19/IL15-Transduced CB-NK Cells;   Drug: AP1903
Sponsors:   M.D. Anderson Cancer Center;   Bellicum Pharmaceuticals
Not yet recruiting - verified April 2017

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