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Clinical Trials: Cord Blood

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Body: Conditions:   CD19 Positive;   Mantle Cell Lymphoma;   Recurrent Diffuse Large B-Cell Lymphoma;   Recurrent Follicular Lymphoma;   Refractory B-Cell Non-Hodgkin Lymphoma;   Refractory Diffuse Large B-Cell Lymphoma;   Refractory Follicular Lymphoma
Interventions:   Procedure: Autologous Hematopoietic Stem Cell Transplantation;   Drug: Carmustine;   Drug: Cytarabine;   Drug: Etoposide;   Biological: Filgrastim;   Drug: Melphalan;   Biological: Rituximab;   Biological: Umbilical Cord Blood-derived Natural Killer Cells
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
Not yet recruiting
Body: Conditions:   Bone Marrow Failure Syndrome;   Thalassemia;   Sickle Cell Disease;   Diamond Blackfan Anemia;   Acquired Neutropenia in Newborn;   Acquired Anemia Hemolytic;   Acquired Thrombocytopenia;   Hemophagocytic Lymphohistiocytoses;   Wiskott-Aldrich Syndrome;   Chronic Granulomatous Disease;   Common Variable Immunodeficiency;   X-linked Lymphoproliferative Disease;   Severe Combined Immunodeficiency;   Hurler Syndrome;   Mannosidosis;   Adrenoleukodystrophy
Interventions:   Drug: Thiotepa--single daily dose;   Drug: Thiotepa--escalated dose
Sponsor:   University of Florida
Not yet recruiting
Body: Conditions:   Acute Myeloid Leukemia;   Acute Lymphoblastic Leukemia in Remission;   Myelodysplastic Syndromes;   Other Acute Leukemias
Interventions:   Biological: Unmanipulated Umbilical Cord Blood (UCB);   Biological: AB-110
Sponsor:   Angiocrine Bioscience
Not yet recruiting
Body: Condition:   Cerebral Palsy
Interventions:   Biological: Infusion of allogeneic umbilical cord blood;   Biological: Infusion of MSCs
Sponsors:   Joanne Kurtzberg, MD;   The Marcus Foundation
Not yet recruiting
Body: Condition:   Multiple Myeloma
Intervention:   Biological: ECT-001 (UM171) expanded cord blood
Sponsors:   Ciusss de L'Est de l'Île de Montréal;   ExcellThera;   Centre de Commercialisation en Immunothérapie du Cancer (C3i)
Not yet recruiting
Body: Conditions:   Acute Myeloid Leukemia;   Acute Lymphoblastic Leukemia;   Acute Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic-Myeloproliferative Diseases;   Myeloproliferative Disorder;   Non Hodgkin Lymphoma;   Hodgkin Lymphoma;   Leukemia
Interventions:   Radiation: Total Body Irradiation;   Drug: Cyclosporine;   Drug: Mycophenolate Mofetil;   Drug: Tocilizumab;   Drug: Filgrastim
Sponsor:   Memorial Sloan Kettering Cancer Center
Recruiting
Body: Conditions:   Hypoplastic Left Heart Syndrome;   Heart Defects, Congenital;   Pediatric Disorder
Intervention:   Biological: Autologous Human Placental Cord Blood Mononuclear Cells
Sponsor:   Murdoch Childrens Research Institute
Not yet recruiting
Body: Condition:   Inherited Metabolic Disorders (IMD)
Intervention:   Drug: MGTA-456
Sponsor:   Magenta Therapeutics, Inc.
Not yet recruiting
Body: Conditions:   Acute Biphenotypic Leukemia;   Acute Lymphoblastic Leukemia in Remission;   Acute Myeloid Leukemia in Remission;   Blasts Under 10 Percent of Bone Marrow Nucleated Cells;   Blasts Under 5 Percent of Bone Marrow Nucleated Cells;   Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Cytogenetic Abnormality;   High Risk Myelodysplastic Syndrome;   Myelodysplastic Syndrome With Excess Blasts;   Pancytopenia;   Refractory Anemia
Interventions:   Drug: Cyclophosphamide;   Drug: Fludarabine;   Other: Laboratory Biomarker Analysis;   Drug: Thiotepa;   Radiation: Total-Body Irradiation;   Biological: Umbilical Cord Blood-derived Hematopoietic CD34-positive Progenitor Cells;   Procedure: Umbilical Cord Blood Transplantation
Sponsors:   Fred Hutchinson Cancer Research Center;   National Cancer Institute (NCI);   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting
Body: Conditions:   Myelodysplastic Syndromes;   Leukemia, Myeloid, Acute;   Leukemia, Relapsed Adult Acute Myeloid;   Myelodysplastic Syndromes, Previously Treated
Interventions:   Drug: CPX-351;   Drug: Fludarabine;   Drug: Melphalan;   Drug: Rabbit Anti-Human T-Lymphocyte Globulin;   Biological: Haplo-Cord Stem Cell Transplantation
Sponsor:   Weill Medical College of Cornell University
Recruiting
Body: Condition:   Severe Bronchopulmonary Dysplasia
Interventions:   Biological: PNEUMOSTEM;   Other: Placebo
Sponsor:   Medipost Co Ltd.
Not yet recruiting
Body: Conditions:   Diabetes Mellitus, Type 1;   Diabetes Mellitus, Type 2
Intervention:   Combination Product: Stem Cell Educator therapy
Sponsors:   Tianhe Stem Cell Biotechnologies Inc.;   Chinese PLA General Hospital
Recruiting
Body: Condition:   Bronchopulmonary Dysplasia
Interventions:   Drug: transplantation of mesenchymal stem cell;   Drug: no transplantation of mesenchymal stem cell
Sponsors:   Daping Hospital and the Research Institute of Surgery of the Third Military Medical University;   Children's Hospital of Chongqing Medical University;   Chongqing Maternal and Child Health Hospital
Recruiting
Body: Conditions:   Severe Aplastic Anemia;   Hypo-Plastic MDS;   Myelodysplastic Syndrome (MDS)
Intervention:   Biological: CordIn(TM)
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified April 18, 2017
Body: Condition:   Alzheimer's Disease
Interventions:   Biological: human umbilical cord blood derived mesenchymal stem cells;   Other: Normal saline 2mL
Sponsor:   Medipost Co Ltd.
Recruiting - verified May 2017

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