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Clinical Trials: Cord Blood


Body: Condition:   Cerebral Palsy
Intervention:   Biological: Matched sibling donor cord blood cell infusion
Sponsors:   Murdoch Childrens Research Institute;   The Royal Children's Hospital Melbourne;   Children's Health Queensland;   Monash Health;   Sydney Children's Network;   Cerebral Palsy Alliance
Recruiting - verified March 2017
Body: Conditions:   Acute Myeloid Leukemia;   Acute Lymphocytic Leukemia;   Myelodysplastic Syndrome;   Non-hodgkin Lymphoma;   Chronic Lymphocytic Leukemia
Interventions:   Drug: Cyclophosphamide;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Other: Haploidentical Stem Cell Transplantation
Sponsor:   Loyola University
Recruiting - verified March 2017
Body: Conditions:   B-Lymphoid Malignancies;   Acute Lymphocytic Leukemia;   Chronic Lymphocytic Leukemia;   Non-hodgkin Lymphoma
Interventions:   Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Mesna;   Biological: iC9/CAR.19/IL15-Transduced CB-NK Cells;   Drug: AP1903
Sponsors:   M.D. Anderson Cancer Center;   Bellicum Pharmaceuticals
Not yet recruiting - verified April 2017
Body: Condition:   B-Cell Non-Hodgkin Lymphoma
Interventions:   Biological: NK Cells;   Drug: Rituximab;   Drug: Carmustine;   Drug: Etoposide;   Drug: Cytarabine;   Drug: Melphalan;   Drug: Lenalidomide 10Mg Capsule;   Drug: G-CSF;   Biological: Auto SCT;   Other: Apheresis
Sponsor:   M.D. Anderson Cancer Center
Not yet recruiting - verified March 2017
Body: Conditions:   Acute Leukemia;   Immune Deficiency Disorder;   Congenital Hematological Disorder;   Metabolism Disorder;   Aplastic Anemia;   Myelodysplastic Syndromes;   Chronic Leukemia;   Lymphoma;   Multiple Myeloma;   Solid Tumor
Interventions:   Radiation: Total Body Irradiation 1200 cGy;   Radiation: Total Body Irradiation 200 cGy;   Drug: Cyclophosphamide;   Drug: Mesna;   Procedure: Cord Blood Infusion;   Drug: Busulfan;   Drug: Fludarabine;   Drug: Melphalan
Sponsor:   University of Rochester
Body: Conditions:   Stroke;   Stroke, Acute;   Brain Injury, Acute
Interventions:   Biological: Umbilical Cord Blood;   Other: Placebo
Sponsors:   Joanne Kurtzberg, MD;   The Marcus Foundation;   Emory University;   M.D. Anderson Cancer Center
Recruiting - verified March 2017
Body: Condition:   Severe Aplastic Anemia
Interventions:   Drug: Antithymocyte Globulin;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Radiation: Total Body Irradiation (TBI);   Procedure: UCB HSCT;   Procedure: Haplo HSCT;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil (MMF);   Drug: G-CSF
Sponsors:   Medical College of Wisconsin;   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI);   Blood and Marrow Transplant Clinical Trials Network;   National Marrow Donor Program
Recruiting - verified August 2017
Body: Condition:   Cell Transplantation
Interventions:   Drug: Pneumostem;   Drug: Normal saline
Sponsor:   Samsung Medical Center
Recruiting - verified April 2017
Body: Conditions:   Hematological Malignancies;   Acute Lymphoblastic Leukemia (ALL);   Acute Myelogenous Leukemia (AML);   Chronic Myelogenous Leukemia (CML);   Myelodysplastic Syndrome (MDS)
Interventions:   Drug: NiCord®;   Other: Cord Blood Unit
Sponsor:   Gamida Cell ltd
Recruiting - verified December 2016
Body: Condition:   Inherited Metabolic Disorders (IMD)
Intervention:   Drug: Umbilical cord blood transplantation with HSC835
Sponsor:   Novartis Pharmaceuticals
Not yet recruiting - verified March 2017
Body: Condition:   Hematologic Malignancy
Intervention:   Biological: Transplantation of cord blood expanded with UM171
Sponsors:   Maisonneuve-Rosemont Hospital;   Canadian Cancer Society Research Institute (CCSRI);   Canadian Institutes of Health Research (CIHR);   Hopital de l'Enfant-Jesus;   Vancouver General Hospital;   St. Justine's Hospital
Recruiting - verified March 2017
Body: Condition:   Lymphoma
Interventions:   Procedure: Allogeneic stem cell transplantation;   Drug: Fludarabine;   Drug: Thiotepa;   Drug: Methotrexate
Sponsors:   Massachusetts General Hospital;   Adienne SA;   Dana-Farber Cancer Institute
Withdrawn - verified March 2017
Body: Condition:   Hematologic Neoplasms
Intervention:   Procedure: Allogeneic (Allo) hematopoietic stem cell transplantation
Sponsor:   Institut Paoli-Calmettes
Recruiting - verified March 2017
Body: Conditions:   Acute Myeloid Leukemia;   Myelodysplastic Syndrome
Interventions:   Biological: haplo-identical cells (donor);   Biological: umbilical cord blood unit (CBU)
Sponsor:   Weill Medical College of Cornell University