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Clinical Trials: Cord Blood

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Body: Condition:   Severe Combined Immunodeficiency
Interventions:   Biological: unrelated BM with T cell depletion;   Biological: unrelated cord blood;   Biological: haplo BM with T cell depletion;   Device: unrelated PBSC with T cell depletion
Sponsor:   Neena Kapoor, M.D.
Terminated
Body: Conditions:   Sickle Cell Disease;   Sickle Cell Anemia;   SCD
Interventions:   Drug: Fludarabine;   Procedure: Hematopoietic Stem Cell Transplant (HSCT)
Sponsor:   Case Comprehensive Cancer Center
Recruiting - verified July 2017
Body: Condition:   Alzheimer's Disease
Interventions:   Biological: human umbilical cord blood derived mesenchymal stem cells;   Other: Normal saline 2mL
Sponsor:   Medipost Co Ltd.
Recruiting - verified April 2017
Body: Condition:   Crohn's Disease
Intervention:   Biological: Stem cells
Sponsor:   Kang Stem Biotech Co., Ltd.
Recruiting - verified September 2016
Body: Condition:   Cerebral Palsy
Interventions:   Biological: Autologous Stem Cells;   Other: Saline Infusion (Placebo)
Sponsors:   The University of Texas Health Science Center, Houston;   Cord Blood Registry, Inc.;   Let's Cure CP Foundation;   Mission Connect, a program of TIRR Foundation
Active, not recruiting - verified June 2017
Body: Conditions:   Primary Immunodeficiency Syndromes;   Congenital Bone Marrow Failure Syndromes;   Inherited Metabolic Disorders (IMD);   Hereditary Anemias;   Patients With Sickle Disease Presenting Specific Symptoms
Interventions:   Drug: Hydroxyurea;   Drug: Alemtuzumab;   Drug: Fludarabine;   Drug: Melphalan;   Drug: Thiotepa
Sponsor:   University of Pittsburgh
Recruiting - verified March 2017
Body: Conditions:   EBV;   CMV;   Adenovirus
Interventions:   Drug: CTL for CMV seropositive donors;   Drug: CTL for CMV naïve donors
Sponsor:   Catherine Bollard
Recruiting - verified May 2017
Body: Conditions:   Chronic Graft Versus Host Disease;   Chronic GVHD;   Complications of Organ Transplant Stem Cells
Interventions:   Other: Treg-enriched infusion;   Drug: Interleukin-2
Sponsors:   Dana-Farber Cancer Institute;   Miltenyi Biotec GmbH;   Prometheus Laboratories;   National Cancer Institute (NCI)
Recruiting - verified July 2017
Body: Conditions:   Single Umbilical Cord Blood Transplantation;   Non-myeloablative Conditioning;   Acute Lymphocytic Leukemia;   Myelodysplastic Syndrome;   Non-Hodgkin's Lymphoma;   Multiple Myeloma;   Chronic Lymphocytic Leukemia
Intervention:   Drug: HSC835
Sponsor:   Novartis Pharmaceuticals
Completed - verified July 2017
Body: Condition:   Blood And Marrow Transplantation
Intervention:   Drug: Eltrombopag
Sponsors:   M.D. Anderson Cancer Center;   Novartis Pharmaceuticals
Recruiting - verified April 2017
Body: Condition:   Bronchopulmonary Dysplasia
Interventions:   Biological: Pneumostem®;   Biological: normal saline
Sponsor:   Medipost Co Ltd.
Recruiting - verified April 2017
Body: Condition:   Hypoplastic Left Heart Syndrome
Intervention:   Biological: autologous cell-based delivery
Sponsors:   Timothy J. Nelson;   University of Oklahoma;   Children's Hospital of Philadelphia
Recruiting - verified June 2017
Body: Conditions:   GATA2;   Immunodeficiency;   MDS
Interventions:   Procedure: Allogeneic HSC;   Drug: Busulfan Test dose;   Drug: Fludarabine(Fludara, Berlex Laboratories);   Drug: Busulfan (Busulfex);   Drug: Cyclophosphamide(CTX, Cytoxan);   Procedure: Total Body Irradiation (TBI);   Drug: Equine Anti-Thymocyte Globulin
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified January 31, 2017
Body: Conditions:   Aplastic Anemia;   Leukemia;   Myelodysplastic Syndrome (MDS);   Lymphoma
Intervention:   Procedure: Cord Blood Units
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI);   National Institute of Allergy and Infectious Diseases (NIAID);   National Cord Blood Program, New York Blood Center
Recruiting - verified January 12, 2017
Body: Condition:   Hypoplastic Left Heart Syndrome (HLHS)
Intervention:   Other: Collection of umbilical cord blood
Sponsor:   Mayo Clinic
Recruiting

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