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Clinical Trials: Cord Blood

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Body: Conditions:   Leukemia;   Lymphoma
Interventions:   Drug: Rituximab;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Radiation: Total Body Radiation;   Procedure: Fucosylated Regulatory T Cells;   Procedure: Cord Blood Infusions;   Drug: Mycophenolate mofetil;   Drug: Sirolimus;   Procedure: Bone Marrow Aspiration;   Drug: G-CSF;   Procedure: Non-Fucosylated Regulatory T Cells
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI);   Targazyme, Inc.;   Cancer Prevention Research Institute of Texas
Recruiting - verified April 2017
Body: Condition:   Stroke
Intervention:   Biological: allogeneic umbilical cord blood
Sponsor:   Joanne Kurtzberg, MD
Completed - verified March 2017
Body: Conditions:   Sickle Cell Disease;   Thalassemia
Intervention:   Biological: CordIn
Sponsor:   Gamida Cell ltd
Recruiting - verified September 2016
Body: Condition:   Metabolic Disorders
Intervention:   Biological: ProHema-CB Transplant
Sponsor:   Fate Therapeutics
Terminated - verified October 2015
Body: Condition:   Leukemia, Myeloid
Interventions:   Drug: IV Thiotepa;   Drug: IV Fludarabine;   Drug: IV Busulfan;   Drug: IV Anti-thymocyte globuline
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting
Body: Condition:   Acute Myeloid Leukemia
Interventions:   Drug: chemotherapy (Mitoxantrone, Cytarabine);   Drug: Placebo;   Drug: Crenolanib;   Other: Allogeneic stem cell transplantation
Sponsor:   University of Ulm
Recruiting - verified March 2017
Body: Condition:   Mesenchymal Stromal Cells
Intervention:   Drug: pneumostem
Sponsor:   Samsung Medical Center
Completed - verified April 2017
Body: Conditions:   Primary Myelofibrosis;   Secondary Myelofibrosis
Interventions:   Procedure: Allogeneic Hematopoietic Stem Cell Transplantation;   Drug: Busulfan;   Drug: Cyclophosphamide;   Drug: Fludarabine Phosphate;   Other: Laboratory Biomarker Analysis;   Drug: Melphalan;   Drug: Methotrexate;   Drug: Momelotinib;   Drug: Mycophenolate Mofetil;   Drug: Pacritinib;   Drug: Ruxolitinib;   Drug: Tacrolimus;   Radiation: Total-Body Irradiation;   Procedure: Umbilical Cord Blood Transplantation
Sponsors:   Fred Hutchinson Cancer Research Center;   National Cancer Institute (NCI);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified May 2017
Body: Condition:   Hematological Malignancies
Interventions:   Drug: Cyclophosphamide;   Drug: Thiotepa;   Drug: Fludarabine;   Drug: Melphalan;   Drug: Mesna;   Biological: G-CSF;   Drug: Mycophenolate mofetil;   Drug: Tacrolimus;   Drug: Methylprednisolone;   Radiation: Total lymphoid irradiation;   Biological: Lymphocyte infusions;   Device: CliniMACS
Sponsor:   St. Jude Children's Research Hospital
Recruiting - verified August 2016
Body: Conditions:   Sickle Cell Disease;   Transfusion Dependent Alpha- or Beta- Thalassemia;   Diamond Blackfan Anemia;   Paroxysmal Nocturnal Hemoglobinuria;   Glanzmann Thrombasthenia;   Severe Congenital Neutropenia;   Shwachman-Diamond Syndrome;   Non-Malignant Hematologic Disorders
Interventions:   Drug: Reduced Toxicity Ablative Regimen;   Drug: Reduced Intensity Preparative Regimen;   Drug: Myeloablative Preparative Regimen
Sponsor:   Masonic Cancer Center, University of Minnesota
Recruiting
Body: Condition:   Severe Combined Immunodeficiency
Interventions:   Biological: unrelated BM with T cell depletion;   Biological: unrelated cord blood;   Biological: haplo BM with T cell depletion;   Device: unrelated PBSC with T cell depletion
Sponsor:   Neena Kapoor, M.D.
Terminated
Body: Conditions:   Sickle Cell Disease;   Sickle Cell Anemia;   SCD
Interventions:   Drug: Fludarabine;   Procedure: Hematopoietic Stem Cell Transplant (HSCT)
Sponsor:   Case Comprehensive Cancer Center
Recruiting - verified July 2017
Body: Condition:   Alzheimer's Disease
Interventions:   Biological: human umbilical cord blood derived mesenchymal stem cells;   Other: Normal saline 2mL
Sponsor:   Medipost Co Ltd.
Recruiting - verified April 2017
Body: Condition:   Crohn's Disease
Intervention:   Biological: Stem cells
Sponsor:   Kang Stem Biotech Co., Ltd.
Recruiting - verified September 2016
Body: Condition:   Cerebral Palsy
Interventions:   Biological: Autologous Stem Cells;   Other: Saline Infusion (Placebo)
Sponsors:   The University of Texas Health Science Center, Houston;   Cord Blood Registry, Inc.;   Let's Cure CP Foundation;   Mission Connect, a program of TIRR Foundation
Active, not recruiting - verified June 2017

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