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Keystone Symposia
Meeting report for Stem Cell Differentiation and dedifferentiation
Place: Keystone, CO
Date: 15th to 20th February 2010
Keystone Symposia has served the bioscience community for 38 years by providing a forum to publicise high quality scientific data in a relaxing environment conducive to the establishment of links between researchers. One of the best features of Keystone meetings is that they are not too large and one gets a chance to talk to some of the best researchers in the field and more often than not they are willing to share as yet unpublished results. The current meeting which took place in the Keystone conference centre was no exception to this.
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The fountain of youth; Choose your partner wisely.
By Carla B. Mellough
The secret to eternal youth has been under pursuit for centuries. But now, results reported in Nature by a group at Harvard University shed new light on just how the ageing process might be co-ordinated across tissues and, astonishingly, that we may be able to reverse it (Mayack et al., 2010).
It’s DNA methylation Jim, but Not As We Know It!
By Stuart P. Atkinson
DNA methylation is an epigenetic mechanism which allows the regulation of gene expression, genome structure and genome stability. Current dogma dictates that DNA methylation mainly occurs on cytosines at CG di-nucleotides, which are found clustered together forming dense patches within the genome. Such regions are known as CpG islands and usually coincide with regulatory regions in promoter sequences, with methylation of cytosines within these regions positively correlated to gene repression. Previous studies of DNA methylation status of various cell types have provided snapshots of this epigenetic modification having mainly concerned themselves with analysing the DNA methylation status of these CpG islands.
Alarm bells for iPSC?
by Lyle Armstrong
Induced pluripotent Stem Cells (iPSC) are widely believed to share many of the characteristics of Embryonic Stem Cells (ESC) and as such have been credited with the potential to revolutionise regenerative medicine. The potential benefit of iPSC exists because of their genetic similarity to the individual from whom they were derived, implying that if differentiated and clinically useful cell types produced from iPSC were transplanted back into the individual, the likelihood of immune rejection should be greatly reduced.
Successful Stem Cell Therapy for Treatment of Eye Disease
NEWCASTLE, United Kingdom, Dec. 10 /PRNewswire/ -- Newly published research, by investigators, at the North East England Stem Cell Institute (NESCI) in the journal STEM CELLS reported the first successful treatment of eight patients with "Limbal Stem Cell Deficiency" (LSCD) using the patients' own stem cells without the need of suppressing their immunity.
Okinawa Institute of Science and Technology (OIST) Workshop
‘Keeping an eye on Neural Stem Cells in light of Photoreceptor Degeneration’
Intensive research efforts worldwide have now brought us closer to understanding how we might drive the differentiation of stem cells towards functional somatic phenotypes and improve cellular integration for visual reconstitution in various forms of retinal degeneration.
Virus Free iPSC – give them the right tools and they’ll do the job!
Stuart P. Atkinson
Induced Pluripotent stem cells (iPSCs) have the potential to revolutionise stem cell biology and regenerative medicine.
STEM CELLS Promotes Miodrag Stojković to Editor
Durham, NC, & Craigavon, UK, July 1, 2009 – AlphaMed Press, co-publisher of the journal STEM CELLS®, the first journal in the field of stem cells and regenerative medicine, has promoted Miodrag Stojković to Editor.
Page 1 of 2
<< Start < Prev 1 2 Next > End >>
It gives me great pleasure to announce that the new Stem Cells Portal became active on Sunday 7th February 2010. This important development will allow us to create an online community of scientists actively engaged in stem cell research and other individuals who are interested in the scientific, ethical, commercial and social impact of this important technology. Our objective in launching the portal is to create a virtual meeting space where persons with relevant questions, comments or even just some issue they need to share with others can come together to discuss the latest developments in the field. We want researchers to feel as comfortable talking with their peers through the portal as they would in their morning lab meetings – the only difference is we can´t provide the coffee!
It is early days in the Portal´s development so we would ask users to bear with us while we add content. As time passes you will notice that more information will appear such as features describing key Stem Cell laboratories, reports of conference proceedings and relevant articles from the scientific and general press but a lot of the Portal content will be influenced by you, the users, so please get involved! Register today and make your opinions count in the world of Stem Cells.
Lyle Armstrong
Stem Cells Portal Editor
Keystone Symposia
Meeting report for Stem Cell Differentiation and dedifferentiation
Place: Keystone, CO
Date: 15th to 20th February 2010
Keystone Symposia has served the bioscience community for 38 years by providing a forum to publicise high quality scientific data in a relaxing environment conducive to the establishment of links between researchers. One of the best features of Keystone meetings is that they are not too large and one gets a chance to talk to some of the best researchers in the field and more often than not they are willing to share as yet unpublished results. The current meeting which took place in the Keystone conference centre was no exception to this.
The fountain of youth; Choose your partner wisely.
By Carla B. Mellough
The secret to eternal youth has been under pursuit for centuries. But now, results reported in Nature by a group at Harvard University shed new light on just how the ageing process might be co-ordinated across tissues and, astonishingly, that we may be able to reverse it (Mayack et al., 2010).
It’s DNA methylation Jim, but Not As We Know It!
By Stuart P. Atkinson
DNA methylation is an epigenetic mechanism which allows the regulation of gene expression, genome structure and genome stability. Current dogma dictates that DNA methylation mainly occurs on cytosines at CG di-nucleotides, which are found clustered together forming dense patches within the genome. Such regions are known as CpG islands and usually coincide with regulatory regions in promoter sequences, with methylation of cytosines within these regions positively correlated to gene repression. Previous studies of DNA methylation status of various cell types have provided snapshots of this epigenetic modification having mainly concerned themselves with analysing the DNA methylation status of these CpG islands.
Alarm bells for iPSC?
by Lyle Armstrong
Induced pluripotent Stem Cells (iPSC) are widely believed to share many of the characteristics of Embryonic Stem Cells (ESC) and as such have been credited with the potential to revolutionise regenerative medicine. The potential benefit of iPSC exists because of their genetic similarity to the individual from whom they were derived, implying that if differentiated and clinically useful cell types produced from iPSC were transplanted back into the individual, the likelihood of immune rejection should be greatly reduced.
Successful Stem Cell Therapy for Treatment of Eye Disease
NEWCASTLE, United Kingdom, Dec. 10 /PRNewswire/ -- Newly published research, by investigators, at the North East England Stem Cell Institute (NESCI) in the journal STEM CELLS reported the first successful treatment of eight patients with "Limbal Stem Cell Deficiency" (LSCD) using the patients' own stem cells without the need of suppressing their immunity.
Okinawa Institute of Science and Technology (OIST) Workshop
‘Keeping an eye on Neural Stem Cells in light of Photoreceptor Degeneration’
Intensive research efforts worldwide have now brought us closer to understanding how we might drive the differentiation of stem cells towards functional somatic phenotypes and improve cellular integration for visual reconstitution in various forms of retinal degeneration.
Virus Free iPSC – give them the right tools and they’ll do the job!
Stuart P. Atkinson
Induced Pluripotent stem cells (iPSCs) have the potential to revolutionise stem cell biology and regenerative medicine.
STEM CELLS Promotes Miodrag Stojković to Editor
Durham, NC, & Craigavon, UK, July 1, 2009 – AlphaMed Press, co-publisher of the journal STEM CELLS®, the first journal in the field of stem cells and regenerative medicine, has promoted Miodrag Stojković to Editor.
Page 1 of 2
<< Start < Prev 1 2 Next > End >>|
It gives me great pleasure to announce that the new Stem Cells Portal became active on Sunday 7th February 2010. This important development will allow us to create an online community of scientists actively engaged in stem cell research and other individuals who are interested in the scientific, ethical, commercial and social impact of this important technology. Our objective in launching the portal is to create a virtual meeting space where persons with relevant questions, comments or even just some issue they need to share with others can come together to discuss the latest developments in the field. We want researchers to feel as comfortable talking with their peers through the portal as they would in their morning lab meetings – the only difference is we can´t provide the coffee! It is early days in the Portal´s development so we would ask users to bear with us while we add content. As time passes you will notice that more information will appear such as features describing key Stem Cell laboratories, reports of conference proceedings and relevant articles from the scientific and general press but a lot of the Portal content will be influenced by you, the users, so please get involved! Register today and make your opinions count in the world of Stem Cells.
Lyle Armstrong Stem Cells Portal Editor |
