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Brief reviews of recently published articles, organized by stem cell type.

August 13, 2010 | Pluripotent Stem Cells

By Stuart P. Atkinson

Delineation of the mechanisms by which embryonic stem cells (ESC) remain pluripotent and maintain the ability to differentiate across all germ lineages has attracted many studies which altogether can be consolidated into an information network which combines transcription factors, chromatin and DNA modifications, small RNAs and signal transduction...

August 5, 2010 | Pluripotent Stem Cells

By Stuart P. Atkinson

The potential applications of human embryonic stem cells (hESC) in regenerative medicine are far reaching, but the need for large numbers of these cells requires prolonged in vitro culture which can lead to the accumulation of unwanted genetic changes and potentially, tumorigenicity.

August 4, 2010 | Pluripotent Stem Cells

Widely reported

The US Food and Drug Administration (FDA) has authorised Geron to carry out the world's first clinical trial using human embryonic stem cells (hESC) in patients with acute spinal cord injury. GRNOPC1 contains hESC-...

July 20, 2010 | Pluripotent Stem Cells

Two advance articles in Nature and Nature Biotechnology from the labs of Konrad Hochedlinger, George Daley and Andrew Feinberg have suggested that iPSC retain a “memory” of their initial state, and...

July 5, 2010 | Haematopoetic Stem Cells

Potential Stem Cell Therapy for HIV Reported

From Nature Biotech

An advance online article from Nature Biotechnology reports the creation of genetically modified human hematopoietic stem/progenitor cells which when injected and engrafted in mice confer some resistance to HIV.   Specifically,...

July 5, 2010 | Pluripotent Stem Cells

Human iPSC Generated from Peripheral Blood Cells

From Cell Stem Cell and Stem Cells and Development

Articles in the new edition of Cell Stem Cell and an online advance report from Stem Cells and Development report...

July 5, 2010 | Cancer Stem Cells

A Step Forward In Understanding Melanoma

From Nature and Cell

Two studies, by Roesch et al in Cell and Boiko et al in Nature, have shed more light on the...

July 5, 2010 | Germ Cells

Germline stem cells: Public Row Ensues

From Nature News

Recent correspondence in Nature has brought into question claims of the pluripotent nature of human adult germline stem cells (haGSCs) generated from human testicular tissue ...

July 5, 2010 | Society

New egg screening technique may boost the success rate of IVF

From BBC

A new egg screening technique pioneered by Care Fertility and reported at the European Society of Human Reproduction and Embryology (ESHRE) conference in Rome, can predict genetic problems in 90% of cases. Use of this technique could lead to increases in pregnancy rates from IVF.   Read the entire story...

June 23, 2010 | Society

From New Scientist

 

Also from the the International Society for Stem Cell Research annual meeting in San Francisco, California is a warning to “clinics offering unproven stem-cell treatments”. (Read more here).   This follows hot on the heels from a...

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