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Research in the Hogan lab is focused on the basic mechanisms underlying organogenesis and tissue repair, and how these two processes involve Stem Cells. We study the development, maintenance, and repair of the foregut and lung, using the mouse as a model genetic organism
The Hogan lab also has a long standing interest in the biology of mammalian primordial germ cells - how they are generated, how they reach the gonad and interact with somatic cells, and how they are reprogrammed to give rise to Pluripotent embryonic germ (EG) cells.
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