Press Releases from AlphaMed Press
Stem cells from fat outperform those from bone marrow in fighting disease
Durham, NC — A new study appearing in the current issue of STEM CELLS Translational Medicine indicates that stem cells harvested from fat (adipose) are more potent than those collected from bone marrow in helping to modulate the body’s immune system.
The finding could have significant implications in developing new stem-cell-based therapies, as adipose tissue-derived stem cells (AT-SCs) are far more plentiful in the body than those found in bone marrow and can be collected from waste material from liposuction procedures. Stem cells are considered potential therapies for a range of conditions, from enhancing skin graft survival to treating inflammatory bowel disease.
New stem cell growth strategy could yield better way to treat brain lesions
Durham, NC — Researchers have found a new way to increase the survival of stem cells injected into the brain. The discovery might one day prove useful in developing new treatments for neurological disorders — especially brain lesions, which among other things can provoke seizures and indicate multiple sclerosis or certain forms of cancer.
The study was performed by Sushma Chaubey, Ph.D., and John H. Wolfe, V.M.D., Ph.D., of the Children's Hospital of Philadelphia’s Research Institute and the University of Pennsylvania School of Veterinary Medicine. It appears in the current issue of STEM CELLS Translational Medicine.
Reduced oxygen levels could double neural stem cells’ chance of survival
Durham, NC — Decreasing the amount of oxygen traditionally used when culturing stem cells for use in neurological therapies could drastically affect their survival rate. In fact, it could double it, according to a new study released today in STEM CELLS Translational Medicine.
“Cells are usually cultured in the lab in a 20 percent oxygen environment, a level far removed from the in vivo situation. This is particularly true in the central nervous system, where oxygen tensions — that is, the concentration of oxygen at a specific pressure — are normally around 3 percent,” said Sybil Stacpoole, M.D., Ph.D., lead author on the paper by a team of researchers from the Universities of Cambridge and Edinburgh.
Scientists find way to fast-track production of stem cells that show promise in treating AMD
Durham, NC — Controlling the differentiation of human pluripotent stem cells is the goal of many laboratories, both to study normal human development and to generate cells for transplantation in treating various diseases and conditions. RPE (retinal pigmented epithelial) is one important cell type under investigation as it protects and nourishes the photoreceptors and is vital in maintaining healthy eyesight.
Stem cells might beat drugs in delivering relief faster, more effectively to rheumatoid arthritis sufferers
Durham, NC — Can stem cell therapy outperform a drug commonly considered the gold standard for treating rheumatoid arthritis? A new study in rodents published in the current issue of STEM CELLS Translational Medicine indicates perhaps so.
The findings could lead to a faster, safer, more effective way to bring relief to the up to 70 million people estimated to suffer from this disease worldwide.
Rheumatoid arthritis (RA) is a chronic condition that causes pain, stiffness, swelling and limited motion and function of many joints. While it can affect any joint, RA tends to settle mainly in a patient’s hands and feet. The results can be debilitating.
New method for mass-producing RPE cells paves way to treating age-related blindness
Durham, NC — Scientists have developed a new, simpler way to produce human pluripotent stem cells in quantities large enough that they can be used to develop treatments for age-related macular degeneration — the leading cause of irreversible blindness among the elderly. The results of this new study are published in the current issue of STEM CELLS Translational Medicine.
Age-related macular degeneration (AMD), which affects up to 50 million people worldwide, is associated with the dysfunction and death of retinal pigment epithelial (RPE) cells.
New study shows stem cells’ promise as future ALS treatment
Durham, NC — A new study in the current issue of STEM CELLS Translational Medicine demonstrates how human stem cells can successfully engraft, survive and differentiate into mature neurons in the spinal cord of a rat with amyotrophic lateral sclerosis (ALS). The results offer new hope for those suffering from this disease, which generally ends in death within three to five years after diagnoses.
New way to mass-produce natural cancer-killing cells offers hope for patients
Durham, NC — In a new study published by STEM CELLS Translational Medicine, scientists report on a way to produce natural cancer-killing cells in the lab in a quantity that could one day make them viable for treating patients.
While the production of human natural killer (NK) cells in the lab from human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) has become routine, it’s been on a limited scale. But this study shows how to increase the number of resulting cells while also reducing the amount of work and time involved in producing them.
- Stem cells produce compact, regenerated bone in mandible transplants
- ALS patients’ own stem cells show promise as a future treatment option
- Stem Cells Show Promise in Extending Transplanted Kidneys’ Survival Time
- Stem cells finding could one day lead to halt of deadly heart complication in Duchenne MD
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