Researchers in Germany have discovered that a tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease. The finding suggests that targeting this protein could be an effective treatment for certain AML patients.
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Coverage of the latest news and updates from ongoing clinical trials from various sources.
Adult stem cells collected directly from human fat are more stable than other cells – such as fibroblasts from the skin – and have the potential for use in anti-aging treatments, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.
Research led by scientists at University of California San Francisco and Case Western Reserve University School of Medicine has used brain "organoids" — tiny 3D models of human organs that scientists grow in a dish to study disease — to identify root causes of Miller-Dieker Syndrome (MDS), a rare
Physicians at the Johns Hopkins Kimmel Cancer Center report they have successfully treated 16 patients with a rare and lethal form of bone marrow failure called severe aplastic anemia using partially matched bone marrow transplants followed by two high doses of a common chemotherapy dru
When most cells divide, they simply make more of themselves. But stem cells, which are responsible for repairing or making new tissue, have a choice: They can generate more stem cells or differentiate into skin cells, liver cells, or virtually any of the body's specialized cell types.
The subventricular zone (SVZ) in normal newborns' brains is home to the largest stockpile of neural stem/progenitor cells, with newly generated neurons migrating from this zone to specific regions of the frontal cortex and differentiating into interneurons.
During the "in vivo" reprogramming process, cellular telomeres are extended due to an increase in endogenous telomerase. This is the main conclusion of a new study by a team from the Spanish National Cancer Research Centre (CNIO).
The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin–Madison scientists have identified two proteins found in bone marrow as key regulators of the master cells responsible for making new bone.
Today, a stroke is a leading cause of long-term disability. But in the future, the stroke-injured brain could be reparable by replacing dead cells with new, healthy neurons, using transplantation.
Growing organs from one species in the body of another may one day relieve transplant shortages. Now researchers show that islets from rat-grown mouse pancreases can reverse disease when transplanted into diabetic mice.