All the patients in the trial suffered a stroke between six months and five years before they received the treatment, in which stem cells were injected into the damaged area of the brain.
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Coverage of the latest news and updates from the field of stem cells.
“Ultimately, we want to identify stem cells that can be used as a resource to stimulate tooth renewal in adult humans who have lost teeth. But, to do that, we must first understand how they renew in other animals and why they stop in people,” Dr. Chuong explained.
“To do the best science you need to have the very best scientists, and this award means that CIRM has attracted another six of the top researchers in stem cells and regenerative medicine in the world to California,” says Alan Trounson, Ph.D., president of the stem cell agency.
The problems were initially brought to light on Pubpeer, a website for anonymous comments about published papers.
The technique used by Dr. Mitalipov, Paula Amato, M.D., and their colleagues in OHSU’s Department of Obstetrics & Gynecology, is a variation of a commonly used method called somatic cell nuclear transfer, or SCNT.
“There is a widely held misconception that the adult nervous system is static or fixed, and has a limited capacity for repair and regeneration,” said Dwight Bergles, Ph.D., professor of neuroscience and otolaryngology at the Johns Hopkins University School of Medicine.
“The most amazing thing, which for a little girl is a miracle, is that this transplant has not only saved her life, but it will eventually enable her to eat, drink and swallow, even talk, just like any other normal child,” said Paolo Macchiarini, M.D., Ph.D., professor of regenerative surgery at
When the protein, called GDF-11, was injected into old mice that had developed thickened heart walls in a manner similar to aging humans, the hearts were reduced in size and thickness, resembling the healthy hearts of younger mice.
People with A-T begin life with neurological deficits that become devastating through progressive loss of function in the cerebellum, which leads to severe difficulty with movement and coordination.
“What is unique about this approach is that the native organ’s architecture is preserved, so that the resulting graft can be transplanted just like a donor kidney and connected to the recipient’s vascular and urinary systems,” said Harald Ott, M.D., of the Mass General Center for Regenerative Med