Human and animal trials in which stem cells were injected into cardiac tissue to treat severe heart attacks or substantial heart failure have largely yielded poor results.
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Coverage of the latest news and updates from the field of stem cells.
Neuralstem uses patented technology to produce neural stem cells of the human brain and spinal cord in commercial quantities, with the ability to control the differentiation of these cells constitutively into mature, physiologically relevant human neurons and glia.
Taste cells are located in clusters called taste buds, which in turn are found in papillae, the raised bumps visible on the tongue's surface. Two types of taste cells contain chemical receptors that initiate perception of sweet, bitter, umami, salty and sour taste qualities.
"CIRM embodies the spirit of pioneers in research, setting high standards for others to follow in achieving a wonderful model of collaborative research to improve health," said Mary Woolley, Research!America’s president and CEO.
To date, human kidney cells are extracted directly from human kidney samples. However, this method is inefficient because the samples are limited and the extracted cells die after a few divisions in the petri dish.
This discovery could open the door to a new kind of regenerative medicine.
OMP-52M51 is a proprietary monoclonal antibody that homes in on the Notch1 receptor. It entered clinical testing in hematologic cancers in December and is now also being tested in patients with selected solid tumors.
Previous animal studies have shown that oral intake of DHA (an abundant fatty acid in the brain) reduces Alzheimer-like symptoms. But the new findings, currently published online in Cell Stem Cell, suggest that DHA may be effective only for a subset of patients.
“We believe stem cells are always trying to repair tissue, but they don’t do it well — not because we lack stem cells but, rather, the signals that regulate our stem cells are impaired,” said lead author Marc Penn, M.D., Ph.D., research director at Summa Cardiovascular Institute in Akron, Ohio.
The materials, including the biomedical implantable material polycarbonate plastic, which is a versatile plastic used in things from bulletproof windows to CDs, offer an accessible and cheaper way of culturing hESCs and present new opportunities for future medical research in this area.