NSI-189, the lead compound in Neuralstem's small molecule platform, is a proprietary chemical entity that stimulates new neuron growth in the hippocampus.
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Coverage of the latest news and updates from the field of stem cells.
While stem cells show great promise for treating many medical conditions, tracking their migration and survival following transplantation in the body has been difficult.
"We are now dosing in both the lumbar and cervical regions of the spinal cord for the first time, where the stem cell therapy could support both walking and breathing," said Karl Johe, Ph.D., Neuralstem's chairman and chief scientific officer.
The team has been conducting the PISCES (Pilot Investigation of Stem Cells in Stroke) study, the world's first fully regulated clinical trial of a neural stem cell therapy for disabled stroke patients.
BERKELEY, CALIFORNIA (US), June 6, 2012 — For decades, medical experts have believed that the blocked arteries leading to heart attack and stroke are the result of a deadly combination of cholesterol, fat and the smooth muscle cells within a blood vessel's walls
Several newspapers and scientific web sites were reporting on June 8 that a team of scientists at Yokohama City University, led by Dr. Hideki Taniguchi, successfully transplanted induced pluripotent stem (iPS) cells into the body of a mouse where they began to grow into a human liver.
Multipotent vascular stem cells &mdash a previously unknown type of stem cell &mdash should be the focus in the search for new treatments, the scientists report in the June 6 edition of Nature Communications.
Prior to the study, which is published in the current edition of PLoS ONE, hematopoietic stem cells were thought to have no other option when they went into quiescence and that it was brought on by a lack of nutrients or stimulation.