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Researchers report first lung stem cell transplantation clinical trial

A research team from Tongji University in China have made a breakthrough in human lung regeneration technology. For the first time, researchers have regenerated patients' damaged lungs using autologous lung stem cell transplantation in a pilot clinical trial.

For patients suffering from chronic pulmonary diseases, lung stem cell transplantation could be their best, if not last hope.

Scientists Identify Molecule That May Help Aid Kidney Repair

A new study appearing in STEM CELLS Translational Medicine (SCTM) shows how understanding the way a type of molecule called CD133 functions might contribute to an understanding of the mechanisms involved in kidney repair.

Kidney injuries affect up to 7 percent of hospitalized patients, with those in intensive care especially vulnerable. An increasing amount of evidence indicates that although the kidney might seem to regain normal function, in fact it remains permanently damaged.

What’s the Stem Cells Buzz this Week? – BM-MSCs in Lung Injury Treatment, Fine Tuning PSC Differentiation, Immunomodulation by hiPSC-MSCs, and a Perspective on Digit Tip Regeneration!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Fungal Metabolite Boosts ASC Osteogenesis and Skeletal Regenerative Strategies

Researchers discover that an actin-cytoskeleton modifying fungal metabolite can promote the osteogenesis of adipose stem cells via an epigenetic mechanism

Highlighting Cell-Specific Paths of the Reprogramming Journey

Comparing the reprogramming of somatic cells of different sources helps researchers to delineate universal and cell-specific pieces of the reprogramming process

What’s the Stem Cells Buzz this Week? - Renal Regeneration without Stem Cells, Cell Therapy for Heart Failure, ASC Treatment for Sphincter Injury, and Expansion of UCB-HSPCs!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Vitamin deficiency puts cancer cells into hibernation

Cancer stem cells can be put “into hibernation” by a little-known drug called diphenyleniodonium (DPI) according to researchers from the University of Salford, UK.

DPI effectively switches off the cancer stem cells, preventing their proliferation.

“It’s extraordinary; the cells just sit there as if in a state of suspended animation,” explained Michael Lisanti, M.D., Ph.D., chair of translational medicine and lead investigator.

New mouse model makes stem cells light up green

Scientists at the University of Bonn have found a way to specifically mark multipotent stromal cells, making it possible to analyze their distribution pattern and their function in living organisms.

In order to examine a particular cell type, one must first be able to clearly distinguish it from others. Biologists and physicians have therefore developed sophisticated methods for the live labeling of specific cells. For multipotent stromal cells however, this has until now only been possible to a limited extent.

Researchers gain insight into how the intestine repairs itself

Researchers at Baylor College of Medicine, Johns Hopkins University School of Medicine (Baltimore, Md.) and the University of California, San Francisco have gained new insights into how the small intestine, one of the fastest renewing tissues in the human body, repairs itself after injury caused by intestinal rotavirus infection. Their findings have led them to propose that, contrary to current thinking, how the intestine repairs itself seems to depend on the type of damage.

Discovery may advance neural stem cell treatments for brain disorders

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) is among the first to describe how an mRNA modification impacts the life of neural stem cells (NSCs). The study, published in Nature Neuroscience, reveals a novel gene regulatory system that may advance stem cell therapies and gene-targeting treatments for neurological diseases such as Alzheimer's disease, Parkinson's disease and mental health disorders that affect cognitive abilities.


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