You are here



What’s the Stem Cells Buzz this Week? – Limbal Epithelial Cell Culture, Stem Cell-mediated Tendon Regeneration, Quality-Quantity Stem Cell Culture, and Muscle Stem Cell Regulation via FoxM1!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Stem Cell Discovery Could Aid in Developing Treatments to Control Epileptic Convulsions

A new line of human stem cells shows promise for one day advancing treatment for epileptic seizures. As reported in STEM CELLS Translational Medicine (SCTM), the cells are designed to deliver adenosine – which calms down overexcited neurons and protects them from damage -- to the central nervous system (CNS). The research was conducted by scientists at the University of Bonn and the Central Institute of Mental Health (CIMH) in Mannheim.

What’s the Stem Cells Buzz this Week? - TNF-mediated Stem Cell Fusion, FSTL3-mediated Endothelial Cell Function and Angiogenesis, Definitive Hematopoiesis in iPSCs, and Islet Protection by BMSCs!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Researchers find compound that prevents breast cancer stem cells from activating in the brain

Researchers at Houston Methodist have used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain. They culled through thousands of existing drugs to see if they could identify a compound that would prevent cancer cells from spreading (or metastasizing) and discovered edelfosine, which has been FDA-approved as an investigational leukemia treatment and also used in clinical research for primary brain tumors.

Study suggests smokers needing stem cell therapy would do better with donated cells

Smoking dramatically decreases the regenerative ability of stem cells, according to a study recently published in the journal STEM CELLS. These findings suggest that a smoker in need of stem cell therapy might fare better if the cells he receives are donated by a nonsmoker — counter to the alternative approach of using the patient’s own stem cells whenever possible to reduce the chance of rejection.

Switch discovered that converts blood vessels to stem cells during embryonic development

A switch has been discovered that instructs blood vessel cells to become blood stem cells during embryonic development in mice. Using single-cell technology, researchers from the Wellcome Sanger Institute in Cambridge and the European Molecular Biology Laboratory in Rome discovered that two sets of specific factors in the cells work against each other, and when the balance of these changes the vascular tube cells convert to free blood cells.

Simple and Efficient Protocol Developed to Produce hPSC-Derived Corneal Cells

Researchers describe a quick and effective strategy to derive corneal cells from human pluripotent stem cells and highlight the importance of BMP signaling

2D to 3D Switch Boosts the Regenerative Potential of Cord Blood

A new study demonstrates how a three-dimensional culture substrate can help to maintain the number of primitive stem cells present during the expansion of human cord blood samples

Cell therapy could improve brain function for Alzheimer's disease

Like a great orchestra, your brain relies on the perfect coordination of many elements to function properly. And if one of those elements is out of sync, it affects the entire ensemble. In Alzheimer's disease, for instance, damage to specific neurons can alter brainwave rhythms and cause a loss of cognitive functions.

Mending broken hearts with cardiomyocyte molds

Whether caused by an undetected birth defect or by a heart attack (myocardial infarction), when a heart sustains damage it can be difficult to repair.

If heart muscle cells — cardiomyocytes — could be repaired by cells taken from one’s own body, the patient's recovery improves. But manufacturing heart cells requires an exacting process tailored specifically to an individual.


Subscribe to Stem Cells Portal - Stem Cells Journal Online Community RSS