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HIF-MSC Exosomes: An Efficient and Effective Strategy to Promote Angiogenesis?

A new study indicates that exosomes derived from stem cells overexpressing the HIF-1α transcription factor can promote angiogenesis in vitro and in vivo

How taste cells decide what they want to be

A new study from the Monell Center and collaborating institutions advances understanding of how stem cells on the tongue grow into the different types of mature taste cells that detect either sweet, salty, sour, bitter or umami. By identifying novel genes and molecular pathways involved in shaping a taste cell's function, these findings may someday allow scientists to treat taste disorders, characterize new taste qualities, or even fine-tune a person's taste perception to encourage healthier eating.

Relapse in acute myeloid leukemia traced to rare stem cells

Leukemia researchers led by John Dick, Ph.D., FRS, have traced the origins of relapse in acute myeloid leukemia (AML) to rare therapy-resistant leukemia stem cells that are already present at diagnosis and before chemotherapy begins.

They have also identified two distinct stem cell-like populations from which relapse can arise in different patients in this aggressive cancer that they previously showed starts in blood stem cells in the bone marrow.

Stem cells show promise in treating asthma

A study led by scientists at Monash University has shown that a new therapy developed through stem cell technology holds promise as a treatment for chronic asthma.

From Exploring CGI Protection to Epigenomic Editing in Pluripotent Stem Cells

A study exploring DNA methylation processes has uncovered an exciting new means to edit the epigenome in pluripotent stem cells

MSC-based Neo Islets: The Future of Long Term Diabetes Control?

A new study describes how Neo Islets composed of mesenchymal stem cells and allogeneic islet cells may be the future of type I diabetes treatment

iPSC-MSC in vivo Study Uncovers Novel Immunomodulatory Mechanism

Researchers studying the effects of iPSC-MSCs treatment in an in vivo mouse model discover a novel immunomodulatory mechanism involving caspase proteins

Hitting the bullseye on cancer stem cells

Researchers have identified a unique feature of cancer stem cells that can be exploited to kill the deadly cells thought to be the reason that cancer comes back after therapy. Understanding this feature will be useful for delivering more targeted cancer therapeutics to the right patients.

Study Pinpoints Best Stage of Stem Cell Differentiation for Use in Treating Parkinson’s Disease

DURHAM, NC - Studies indicate that replacing damaged brain cells with those derived from human embryonic stem cells might lead to an effective treatment for Parkinson’s disease. But what has not been determined is the optimal stage during differentiation of the stem cells that the transplantation should take place to gain the best results.

What’s the Stem Cells Buzz this Week? - Regenerating the Diabetic Heart, Tissue Repair with Stem Cell-EVs, ESC-Derived Dopaminergic Neurons, and Trialing ADRCs for Breast Cancer-Related Lymphedema!

A roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond brought to you by the Stem Cells Portal!

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