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Application of New Human ESC Reporter Cell Line Enhances Differentiation of Important Retinal Cells

Researchers have improved the differentiation of RGCs by creating a new and improved reporter human ESC line generated via CRISPR/Cas9 genome editing 

Cell Volume modulates Mesenchymal Stem Cell Fate

Researchers studying microenvironmental influences on cell mechanics highlight a link between changes in cell volume and the differentiation potential of mesenchymal stem cells

 

What’s the Stem Cells Buzz this Week? – Inflammatory Cycling in MSCs, Slimming-down MSCs with Vesicles, Boosting Bone and Cartilage Regeneration, and Trialing Autologous Cord Blood!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Stem cells used to repair myocardial infarctions in rats

Researchers from the Institute for Integrated Cell-Material Sciences (iCeMS) of Kyoto University and the Department of Cardiovascular Surgery of Osaka University have developed effective and convenient cardiac tissue-like constructs (CTLCs) for repairing myocardial infarctions.

What’s the Stem Cells Buzz this Week? - ASC-mediated Vasculogenesis, Inhibition of PSC Tumorigenesis, Stem Cells and Cancer, and MSC Characterization!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Method discovered for accelerating maturation of stem cells to form neurons

Researchers at the University Medical Center of Johannes Gutenberg University Mainz (JGU) have developed a promising technique to facilitate the differentiation of stem cells into neurons. This even enables them to accelerate the maturation process.

To do this, they used a hydrogel to create a stiffness-controlled scaffold for artificial brain tissue that also stimulates the development of neurons. The team subsequently plans to investigate how hydrogel-based biomaterials can be injected into severely damaged brain regions in order to improve brain tissue regeneration.

Transplanted hematopoietic stem cells reverse damage caused by neuromuscular disorder

Researchers at the University of California San Diego School of Medicine report that a single infusion of wildtype hematopoietic stem and progenitor cells (HSPCs) into a mouse model of Friedreich’s ataxia (FA) measurably halted cellular damage caused by the degenerative disease.

The findings suggest a potential therapeutic approach for a disease that currently is considered incurable.

Long-lasting blood vessel repair in animals via stem cells

Stem cell researchers at Emory University School of Medicine (Atlanta, Georgia) have made an advance toward having a long-lasting "repair caulk" for blood vessels. The research could form the basis of a treatment for peripheral artery disease, derived from a patient's own cells.

Their results were recently published in Circulation.

Long-lasting blood vessel repair in animals via stem cells

Stem cell researchers at Emory University School of Medicine (Atlanta, Georgia) have made an advance toward having a long-lasting "repair caulk" for blood vessels. The research could form the basis of a treatment for peripheral artery disease, derived from a patient's own cells.

Their results were recently published in Circulation.

Cell-Free Amniotic Membrane-derived Hydrogel Boosts Skin Wound Healing

By combining solubilized amniotic membrane into an easy to store and apply hydrogel, researchers have developed a cell-free means to accelerate wound healing

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