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Cell-Free Amniotic Membrane-derived Hydrogel Boosts Skin Wound Healing

By combining solubilized amniotic membrane into an easy to store and apply hydrogel, researchers have developed a cell-free means to accelerate wound healing

Enhancing Cartilage Repair Strategies with ROR2

New research suggests that selecting MSCs based on inducible receptor tyrosine kinase-like orphan receptor 2 expression may lead to enhanced cartilage repair strategies

Antibodies: Replacing Reprogramming Factors and Exploring Pluripotency

A new study suggests that engineered antibodies may facilitate the delineation of pluripotency networks and could represent the future of reprogramming approaches 

What’s the Stem Cells Buzz this Week? - Distal Limb Wound Healing, Dentin-Pulp Tissue Regeneration, Report from the ISCBI, and MSCs Requirement for Survivin!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

What’s the Stem Cells Buzz this Week? - MSC Therapy for BD, Wnt Signaling in Skin Development and Epidermal SCs, miRNAs Inhibit HSC Formation, and an In Vivo Osteogenesis Showdown!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Inflamed support cells appear to contribute to some kinds of autism

Modeling the interplay between neurons and astrocytes derived from children with autism spectrum disorder (ASD), researchers at University of California San Diego School of Medicine, with colleagues in Brazil, say innate inflammation in the latter appears to contribute to neuronal dysfunction in at least some forms of the disease.

Study shows how nerves drive prostate cancer

Researchers at Albert Einstein College of Medicine, part of Montefiore Medicine, report that certain nerves sustain prostate cancer growth by triggering a switch that causes tumor vessels to proliferate. Their earlier research — which first implicated nerves in fueling prostate cancer— has prompted Montefiore-Einstein to conduct a pilot study testing whether beta blockers (commonly used for treating hypertension) can kill cancer cells in tumors of men diagnosed with prostate cancer.

Study shows how growth factor aids stem cells’ ability to regenerate damaged teeth

In a new study published in STEM CELLS Translational Medicine, researchers used a type of platelet-derived growth factor called PDGF-BB that enhances cells’ ability to regenerate dentin-pulp complex.

Bolstering fat cells offers potential new leukemia treatment

Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, according to a new study from McMaster University.

Researchers with the McMaster Stem Cell and Cancer Research Institute found that boosting adipocytes, or fat cells, located in the bone morrow suppressed cancerous leukemia cells but – in a surprise to the research team – induced the regeneration of healthy blood cells at the same time.

New findings explain how UV rays trigger skin cancer

Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the United States in 2017, according to the Centers for Disease Control and Prevention.

A fraction of those melanomas come from pre-existing moles, but the majority of them come from sources unknown – until now.

Researchers at Cornell University (Ithaca, N.Y.) have discovered that when melanocyte stem cells accumulate a sufficient number of genetic mutations, they can become the cells where these cancers originate.

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