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What’s the Stem Cells Buzz this Week? - Exosome Mediated Lung Repair, NSPC Metabolic Regulation, Tenogenic Control by AKT‐mTOR, and Oligodendrocyte Differentiation by AKAP12!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Reprogramming Dysfunctional Endothelial Progenitor Cells with PPARα-laden Microparticles

A new study suggests that PPARα-laden membrane microparticles can reverse loss function of endothelial progenitor cells in a mouse model of metabolic syndrome

New Stem Cell Strategy for Creates Reliable Blood-Brain Barrier Model

The efficient production of specialized endothelial cells from pluripotent stem cells may accelerate the construction of a reliable blood-brain barrier model 

NIH discovery brings stem cell therapy for eye disease closer to the clinic

Scientists at the National Eye Institute (NEI), part of the National Institutes of Health, report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE) — a layer of cells in the back of the eye — are essential for the survival of the retina’s light-sensing photoreceptors. The discovery has advanced efforts to make stem cell-derived RPE for transplantation into patients with geographic atrophy, otherwise known as dry age-related macular degeneration (AMD), a leading cause of blindness in the U.S.

Phase III clinical trials begin for stem cell-based cartilage regeneration therapy

Researchers at Osaka University have developed a synthetic tissue for treating damaged cartilage, which had previously been incurable and had no effective therapies. Their method uses synovium-derived mesenchymal stem cells (MSCs) as the starting material.

Study indicates stem cell transplant is better than drug therapy for scleroderma

Scleroderma with internal organ involvement is a debilitating and lethal autoimmune disorder with few effective treatments. But a study led by Duke Health researchers has found new cause for optimism using an aggressive stem cell transplant regimen.

What’s the Stem Cells Buzz this Week? - NKX2-5 Mutations and CHD, Murine Corneal Renewal, Stem Cell Fate and Chromatin, and Fat-Cancer Cell Interactions!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Intact Cell Mass Spectrometry: Quality Control for Human Embryonic Stem Cells?

Researchers describe a robust and simple means to assess quality control in cultures of human embryonic stem cell cultures: intact cell mass spectrometry fingerprinting

Accelerating Liver Cancer Research with Three Dimensional Tumoroids

A new three-dimensional in vitro model of liver tumorigenesis may provide an efficient means to study cancer development and create new and effective therapies.

MSC-derived Extracellular Vesicles Battle Inflammation with Inflammation!

New research demonstrates how proinflammatory stimuli can promote the production of extracellular vesicles from MSCs with enhanced immunomodulatory capacity.

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