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India proposal would bring stem cells under government regulation

An amendment to India’s Drugs and Cosmetics Act has been proposed by the Union health ministry that would bring stem cells and cell-based products under the scope of the law. Under the proposal, stem cells and their derivatives would need to follow protocols mandated for any new drug development.

Researchers optimize lung stem cell engineering process

The Center for Regenerative Medicine (CReM) at Boston University and Boston Medical Center has engineered two new categories of lung epithelial cells in vitro using pluripotent stem cells. CReM researchers detailed their use of single cell RNA sequencing, a state-of-the-art technique they employed to generate the most comprehensive profile to date of air sack-like (alveolospheres) and airway-like (bronchospheres) cells derived from pluripotent stem cells.

A Safe and Rapid Strategy for Improved Bone Defect Repair by Bone Marrow Stem Cells

Researchers describe a new approach to improve in vivo osteogenesis by bone marrow-derived stem cells and thereby enhance bone defect repair strategies

Setd7 Inhibition: The Way Forward for MuSC-based Therapies for Muscular Dystrophy?

Researchers discover that the inhibition of a lysine methyltransferase allows for the long-culture and amplification of human muscle stem cells

Early stimulation improves performance bioengineered human heart cells

Researchers are now able to use induced pluripotent stem cells (iPSCs) to form a model of human adult-like cardiac muscle by introducing electric and mechanical stimulation at an early stage. Since this muscle is similar to the adult heart, it could serve as a better model for testing the effects of drugs and toxic substances than current tissue-engineered heart models.

The study, performed by scientists at Columbia University, New York City, and funded by the National Institutes of Health, was published recently in Nature.

Bioengineers develop promising technique to build tracheas for implantation

The human trachea, or wind pipe, extends from the voice box to the lungs. Its tubular form provides an open airway for breathing and a moist lining that repels pathogens. Trachea damage as the result of injury or disease can sometimes require that doctors replace a section of the trachea with an implant.

It's all about the (stem cell) neighborhood

Stem cells have the ability to develop, or differentiate, into the many different cell types in the body. They also serve as a repair system to replace aged or damaged cells. With their regenerative abilities, stem cells offer enormous potential in treating many diseases.

Researchers at Duke-NUS Medical School have now identified how the stem cell neighborhood keeps stem cells in the gut alive.

Trial underway to treat AMD-related vision loss via stem cell implants

Age-related macular degeneration (AMD) affects more than 1.75 million individuals in the United States. Because the population is aging, that number will increase to almost 3 million by 2020. Between 80 and 90 percent of cases in this country are the dry version of the condition, for which no effective treatment exists.

'Sleeping' stem cells could aid brain repair

Scientists at the Wellcome Trust/ Cancer Research UK Gurdon Institute, University of Cambridge, have identified a new type of stem cell in the brain which they say has a high potential for repair following brain injury or disease.

What’s the Stem Cells Buzz this Week? - How Cigarette Smoke affects ASCs, MSC-Cancer Cell Cross-talk, Stem Cell Defect in Transgenic Mice, and Gastric Cancer CSCs!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

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