You are here



Bolstering fat cells offers potential new leukemia treatment

Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, according to a new study from McMaster University.

Researchers with the McMaster Stem Cell and Cancer Research Institute found that boosting adipocytes, or fat cells, located in the bone morrow suppressed cancerous leukemia cells but – in a surprise to the research team – induced the regeneration of healthy blood cells at the same time.

New findings explain how UV rays trigger skin cancer

Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the United States in 2017, according to the Centers for Disease Control and Prevention.

A fraction of those melanomas come from pre-existing moles, but the majority of them come from sources unknown – until now.

Researchers at Cornell University (Ithaca, N.Y.) have discovered that when melanocyte stem cells accumulate a sufficient number of genetic mutations, they can become the cells where these cancers originate.

What’s the Stem Cells Buzz this Week? - Single-Cell SSPCs Analysis, Treg-mediated Cancer Cell Stemness, Parthenogenetic ESC-derived Cortical Neurons, and Protection of Retinal Ganglion Cells!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Organ Complementation highlights in vivo Contribution of PSCs to Bone-forming Cells

A study shows how human pluripotent stem cells form functional osteoblasts following transplantation into a mouse embryo engineered to lack a skeletal system

Overcoming infertility with Induced Pluripotent Stem Cell Reprogramming?

Researchers investigating sex chromosome trisomy discover that reprogramming patient cell samples may be an effective means to treat human infertility 

New ‘expanded potential stem cells’ could shed light on developmental disorders

For the first time, researchers have created expanded potential stem cells (EPSCs) in mice that, they report, have a greater potential for development than current stem cell lines. These stem cells have the features of the very first cells in the developing embryo and can develop into any type of cell.

The methods used could also help produce similar stem cell lines from human and other mammalian species, including those such as pigs or cows, where embryonic stem cell lines are still not available.

What’s the Stem Cells Buzz this Week? - CAR T Cell Therapies, Intestinal Stem Cell Fitness, Alveolar Injury treatment with EPCs, and iPSC Neuropsychiatric Disease Models!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Scientists pinpoint melanoma’s origin

A team of researchers has tracked down the cellular origin of cutaneous melanoma, the deadliest form of skin cancer. They observed that these very aggressive tumors arise from mature, pigment-producing cells called melanocytes.

As melanoma develops, these cells are eventually reprogrammed, lose their differentiated features and become invasive, migratory cancer cells. This knowledge is vital to understanding how these melanoma lesions are formed, facilitate their early detection and develop preventive treatment avenues.

Growing human brain cells in the lab

Li Gan, Ph.D., wants to find treatments to help patients with Alzheimer’s disease. Like most researchers, she’s hit a few major roadblocks.

When researchers like Dr. Gan find potential new drugs, it's useful to test them on human cells to increase the chances that they will benefit patients. Historically, these tests have been conducted in cancer cells, which often don’t match the biology of human brain cells.

Battling Lung Fibrosis with Allogeneic Lung Spheroid Cells

In the search for more effective treatment strategies for lung disease, a team of researchers highlights the potential utility of allogeneic adult lung spheroid cells


Subscribe to Stem Cells Portal - Stem Cells Journal Online Community RSS