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Muscle Stem Cells



Setd7 Inhibition: The Way Forward for MuSC-based Therapies for Muscular Dystrophy?

Researchers discover that the inhibition of a lysine methyltransferase allows for the long-culture and amplification of human muscle stem cells

Researchers Discover how Notch Duo Coordinate Muscle Stem Cell Regulation

A new STEM CELLS study describes how two members of the regeneration-associated Notch signaling pathway combine to coordinate muscle stem cell regulation

New Muscle Stem Cell Expansion Technique May Boost Muscle Regeneration Strategies

A new soft fibrin culture substrate permits the selective expansion of muscle stem cells from bulk muscle tissue

Magnetic Sorting Promotes Clinical Applicability of Smooth Muscle Progenitor Cells

A new study describing the magnetic sorting of smooth muscle progenitor cells derived from human induced pluripotent stem cells may promote their clinical application

Investigating the Intracellular Regulators of Muscle Stem Cells

A new study describes the importance of the KLF7 transcription factor in the regulation of muscle stem cell activity

Reversing Muscle Stem Cell Aging with pro-IGF-II?

New research finds that a post-translationally processed isoform of IGF-II may be able to promote muscle regeneration in the elderly by modulating the muscle stem cell microenvironment

Lkb1 - Muscling onto the Stem Cell Scene

Researchers identify a protein kinase vitally important to muscle stem cell function.

Can a Simple Laminin Injection Aid Exercise-Associated Muscle Damage?

Supplementation of a simple laminin protein known to enhance muscle stem cell and overall muscle function may allow for an improved regenerative muscular response to exercise.

Improved Gene Correction Strategy for Muscular Dystrophy Therapeutics

An improved gene correction strategy in muscle stem cells shows encouraging results in a mouse model of Duchene Muscular Dystrophy.

New Players in Wnt-mediated Control of Muscle Growth and Repair

Detailed assays delineate the muscle-specific mechanisms of Wnt signaling in muscle satellite cells through Barx2, Pax7 and myogenic factors, which may lead to strategies to enhance muscle growth and repair.


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