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The potential of stem cells therapies and regenerative medicine is both provocative and powerful, offering the distinct possibility of eventually repairing or replacing tissues damaged from disease, including certain cancers. By helping speed expert translations of emerging lab discoveries into legitimate clinical trials and bedside application, Stem Cells Translational Medicine ultimately will improve patient outcomes.
Stem Cells Translational Medicine welcomes original articles and concise reviews describing the clinically relevant translational aspects of stem cells and progenitor cells for cell based therapy, tissue engineering and regenerative medicine from the bench to patient care. The Journal covers all clinical translational aspects of stem cells. The following sections include, but are not limited to, the topics listed:
Embryonic Stem Cells/Induced Pluripotent Stem (iPS) Cells
- Derivation, characterization and differentiation for clinical use
- Cell banking
- Therapeutic potential
- Animal models
- Translational pre-clinical studies
- Clinical applications
- First in human case studies
- Phase I/II clinical trials
- Negative clinical results
Fetal and Neonatal Stem Cells
- Derivation, characterization and differentiation for clinical use
- Cell banking
- Therapeutic potential
- Animal models
- Translational pre-clinical studies
- Clinical applications
- First in human case studies
- Phase I/II clinical trials
- Negative clinical results
Tissue-Specific progenitor and Stem Cells
- Derivation, characterization and differentiation for clinical use
- Cell banking
- Therapeutic potential
- Animal models
- Translational pre-clinical studies
- Clinical applications
- First in human case studies
- Phase I/II clinical trials
- Negative clinical results
Cell based drug development, screening and toxicology
- Derivation, characterization and differentiation
- In-vivo models
- In-vitro models
- Throughput systems
Enabling technologies for cell based clinical translation
- Cell tracking
- Cell delivery vehicles
- Biomaterials
- Devices
- Imaging
- Diagnostics
Cancer Stem Cells
- Characterization
- Therapeutic targets
- Animal models
- Translational pre-clinical studies
- Clinical applications
- First in human case studies
- Phase I/II clinical trials
- Negative clinical results
Standards, Policies, and Regulations for cell based therapies
- Cell standards
- Intellectual property relevant to clinical translation
- Cell toxicology/ tumorigenesis and other assays
- Regulations for manufacturing
- Regulations for clinical trials
Protocols and manufacturing for cell based therapies
- GMP aspects
- Cell based processing/expansion
- Cell based potency/storage
- Quality assurance/control
- Scale-up and production
- Cell based therapies release criteria
Tissue engineering and regenerative medicine
- Applications for cell-based strategies in pathological conditions
- Tissue engineering
- Medical device and artificial organ development
- Cell transplantation and technologies that will maintain, improve or restore the function of diseased organs
- Therapeutic potential
- Animal models
- Translational pre-clinical studies
- Clinical applications
- First in human case studies
- Phase I/II clinical trials
- Negative clinical results
Download "Call for Papers" PDF
Submit your manuscripts at http://mc.manuscriptcentral.com/stemcellstm
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