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Conditional Knockout ESCs Reveal Cell Survival Role for Gabpa

A new study delineates the role of the tumor-related transcription factor Gabpa in the pluripotency network of mouse embryonic stem cells

New iPSC-model for Common Cause of Blindness Demonstrates Enormous Potential

A new study employs patient samples to develop a new induced pluripotent stem cell model of the dry form of age-related macular degeneration, a common cause of blindness

Application of New Human ESC Reporter Cell Line Enhances Differentiation of Important Retinal Cells

Researchers have improved the differentiation of RGCs by creating a new and improved reporter human ESC line generated via CRISPR/Cas9 genome editing 

Antibodies: Replacing Reprogramming Factors and Exploring Pluripotency

A new study suggests that engineered antibodies may facilitate the delineation of pluripotency networks and could represent the future of reprogramming approaches 

Organ Complementation highlights in vivo Contribution of PSCs to Bone-forming Cells

A study shows how human pluripotent stem cells form functional osteoblasts following transplantation into a mouse embryo engineered to lack a skeletal system

Overcoming infertility with Induced Pluripotent Stem Cell Reprogramming?

Researchers investigating sex chromosome trisomy discover that reprogramming patient cell samples may be an effective means to treat human infertility 

Preclinical Assessment for hESC-derived Oligodendrocyte Progenitor Cells for Cervical Spinal Cord Injury

An exciting new animal study suggests that oligodendrocyte progenitor cells derived from human ESCs are safe for the treatment of cervical spinal cord injury

Comparative Study Highlights Utility of iPSC-derived Cardiomyocytes

A cardiomyocyte showdown suggests that cells derived from different PSC sources demonstrate similar characteristics and functionality following transplantation

TEC-mediated FGF2 Secretion Controls hPSC Pluripotency

A new study describes the discovery of a novel regulator of basic fibroblast growth factor 2-mediated pluripotency

Stem Cell Therapy for Parkinson's Disease - Which Cell is Best?

A comparative study indicates that immature dopaminergic neurons derived from hPSCs represent the ideal cell type for replacement therapy in Parkinson’s Disease

 

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