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TEC-mediated FGF2 Secretion Controls hPSC Pluripotency

A new study describes the discovery of a novel regulator of basic fibroblast growth factor 2-mediated pluripotency

Stem Cell Therapy for Parkinson's Disease - Which Cell is Best?

A comparative study indicates that immature dopaminergic neurons derived from hPSCs represent the ideal cell type for replacement therapy in Parkinson’s Disease

 

Organoid Analysis Highlights the Intercellular Signaling Processes controlling Hepatogenesis

A single-cell RNA sequencing study of liver organoids provides insight into the signaling processes that control three-dimensional organ development 

iPSC-derived Vascular Cells Go with the Flow!

A new study shows that exposure to blood flow hemodynamics can improve the maturation of vascular cells derived from induced pluripotent stem cells

iPSCs and CRISPR/Cas9 Combine to Faithfully Model CoQ10 Deficiency

Two exciting technologies collide to facilitate the modeling of a rare genetic disease and provide a means to discover new treatment strategies

Saving an Endangered Species: iPSC Technology to the Rescue?!

Studies into sex determination using induced pluripotent stem cells leads to a potential strategy to conserve an endangered species

From Exploring CGI Protection to Epigenomic Editing in Pluripotent Stem Cells

A study exploring DNA methylation processes has uncovered an exciting new means to edit the epigenome in pluripotent stem cells

The Safe, Effective, and Non-Invasive Production of Induced Pluripotent Stem Cells from Down Syndrome Patients

A new means to generate Down Syndrome specific iPSCs may lead to enhanced cell-based treatments for associated pathologies and a deeper understanding of disease development

Chemical Cocktail Creates Extended Pluripotent Stem Cells

Researchers describe a new chemical cocktail that enables pluripotent stem cells to form embryonic and extraembryonic tissues

Long-term Neuronal Cell Transplant Study Highlights Long-Distance Neural Growth

A new study finds that progressive electrophysiological and morphological maturation of transplanted iPSC-derived neural cells occurs over long-time periods in vivo

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