While antiviral therapy for AIDS has been successful, new strategies are required to remove the virus from remaining cellular reservoirs. The laboratory of Dan S. Kaufman have now created an engineered pluripotent stem cell derived immune cell to target the suppression of HIV replication. The groups in vitro analyses finds that their engineered cells are more effective than non-engineered, and in vivo analyses shows some promise for the future. Overall, engineering strategies such as this may be the future of patient-specific anti-viral therapeutics.
- Will long term treatment with NK cells abolish HIV infection?
- What other strategies can we adapt to target HIV?
- Is this strategy a viable option for many HIV sufferers?