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Volume 32, Issue 2 - February 2014

Tissue-Specific Stem Cells

An Osteopontin-Integrin Interaction Plays a Critical Role in Directing Adipogenesis and Osteogenesis by Mesenchymal Stem Cells (pages 327–337)
Qing Chen, Peishun Shou, Liying Zhang, Chunliang Xu, Chunxing Zheng, Yanyan Han, Wenzhao Li, Yin Huang, Xiaoren Zhang, Changshun Shao, Arthur I. Roberts, Arnold B. Rabson, Guangwen Ren, Yanyun Zhang, Ying Wang, David T. Denhardt and Yufang Shi
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1567

Cancer Stem Cells

Inhibition of EGFR Induces a c-MET-Driven Stem Cell Population in Glioblastoma(pages 338–348)
Hyun Jung Jun, Roderick T. Bronson and Alain Charest
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1554

Embryonic Stem Cells/Induced Pluripotent Stem Cells

Stimulation of Somatic Cell Reprogramming by ERas-Akt-FoxO1 Signaling Axis(pages 349–363)
Yong Yu, Dan Liang, Qing Tian, Xiaona Chen, Bo Jiang, Bin-Kuan Chou, Ping Hu, Linzhao Cheng, Ping Gao, Jinsong Li and Gang Wang
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1447

HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1–3 and PKM2 (pages 364–376)
Alessandro Prigione, Nadine Rohwer, Sheila Hoffmann, Barbara Mlody, Katharina Drews, Raul Bukowiecki, Katharina Blümlein, Erich E. Wanker, Markus Ralser, Thorsten Cramer and James Adjaye
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1552

Spontaneous Reactivation of Clusters of X-Linked Genes Is Associated with the Plasticity of X-Inactivation in Mouse Trophoblast Stem Cells (pages 377–390)
Agnès Dubois, Jane Lynda Deuve, Pablo Navarro, Sarra Merzouk, Sylvain Pichard, Pierre-Henri Commere, Anne Louise, Danielle Arnaud, Philip Avner and Céline Morey
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1557

Physiological Oxygen Prevents Frequent Silencing of the DLK1-DIO3 Cluster during Human Embryonic Stem Cells Culture (pages 391–401)
Pingyuan Xie, Yi Sun, Qi Ouyang, Liang Hu, Yueqiu Tan, Xiaoying Zhou, Bo Xiong, Qianjun Zhang, Ding Yuan, Yi Pan, Tiancheng Liu, Ping Liang, Guangxiu Lu and Ge Lin
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1558

A Site-Specific Genetic Modification for Induction of Pluripotency and Subsequent Isolation of Derived Lung Alveolar Epithelial Type II Cells (pages 402–413)
Qing Yan, Yuan Quan, Huanhuan Sun, Xinmiao Peng, Zhengyun Zou, Joseph L. Alcorn, Rick A. Wetsel and Dachun Wang
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1570

Loss of Spastin Function Results in Disease-Specific Axonal Defects in Human Pluripotent Stem Cell-Based Models of Hereditary Spastic Paraplegia (pages 414–423)
Kyle R. Denton, Ling Lei, Jeremy Grenier, Vladimir Rodionov, Craig Blackstone and Xue-Jun Li
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1569

Autophagy Regulates Homeostasis of Pluripotency-Associated Proteins in hESCs(pages 424–435)
Yun-Hee Cho, Kyu-Min Han, Dongkyu Kim, Joonsun Lee, Sang-Hee Lee, Kyeng-Won Choi, Jungho Kim and Yong-Mahn Han
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1589

Generation of iPSCs from Genetically Corrected Brca2 Hypomorphic Cells: Implications in Cell Reprogramming and Stem Cell Therapy (pages 436–446)
S. Navarro, V. Moleiro, F.J. Molina-Estevez, M.L. Lozano, R. Chinchon, E. Almarza, O. Quintana-Bustamante, G. Mostoslavsky, T. Maetzig, M. Galla, N. Heinz, B. Schiedlmeier, Y. Torres, U. Modlich, E. Samper, P. Río, J.C. Segovia, A. Raya, G. Güenechea, J.C. Izpisua-Belmonte and J.A. Bueren
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1586

Regenerative Medicine

MMP-10 Is Required for Efficient Muscle Regeneration in Mouse Models of Injury and Muscular Dystrophy (pages 447–461)
Míriam Bobadilla, Neira Sáinz, José Antonio Rodriguez, Gloria Abizanda, Josune Orbe, Alba de Martino, José Manuel García Verdugo, José A. Páramo, Felipe Prósper and Ana Pérez-Ruiz
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1553

Heat Shock Improves Sca-1+ Stem Cell Survival and Directs Ischemic Cardiomyocytes Toward a Prosurvival Phenotype Via Exosomal Transfer: A Critical Role for HSF1/miR-34a/HSP70 Pathway (pages 462–472)
Yuliang Feng, Wei Huang, Wei Meng, Anil G. Jegga, Yigang Wang, Wenfeng Cai, Ha Won Kim, Zeeshan Pasha, Zhili Wen, Fang Rao, Rohan M. Modi, Xiyong Yu and Muhammad Ashraf
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1571

Tissue-Specific Stem Cells

Caspase-3 Modulates Regenerative Response After Stroke (pages 473–486)
Wenying Fan, Yiqin Dai, Haochen Xu, Ximin Zhu, Ping Cai, Lixiang Wang, Chungang Sun, Changlong Hu, Ping Zheng and Bing-Qiao Zhao
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1503

Stromal Cell Derived Factor-1α Promotes C-Kit+ Cardiac Stem/Progenitor Cell Quiescence Through Casein Kinase 1α and GSK3β (pages 487–499)
Neviana Dimova, Marcin Wysoczynski and Gregg Rokosh
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1534

Transplants of Adult Mesenchymal and Neural Stem Cells Provide Neuroprotection and Behavioral Sparing in a Transgenic Rat Model of Huntington's Disease (pages 500–509)
Julien Rossignol, Kyle Fink, Kendra Davis, Steven Clerc, Andrew Crane, Jessica Matchynski, Steven Lowrance, Matthew Bombard, Nicholas DeKorver, Laurent Lescaudron and Gary L. Dunbar
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1508

A Novel Negative Regulator of Adipogenesis: MicroRNA-363 (pages 510–520)
Lin Chen, Junhui Cui, Jia Hou, Jie Long, Cai Li and Lei Liu
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1549

The Toll-like Receptor 3 Ligand, Poly(I:C), Improves Immunosuppressive Function and Therapeutic Effect of Mesenchymal Stem Cells on Sepsis via Inhibiting MiR-143 (pages 521–533)
Xiaoyin Zhao, Dan Liu, Wei Gong, Guangfeng Zhao, Liu Liu, Liu Yang and Yayi Hou
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1543

Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State (pages 534–547)
Eve Kandyba, Virginia M. Hazen, Agnieszka Kobielak, Samantha J. Butler and Krzysztof Kobielak
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1548

Intracellular Reactive Oxygen Species Mark and Influence the Megakaryocyte-Erythrocyte Progenitor Fate of Common Myeloid Progenitors (pages 548–557)
Akihito Shinohara, Yoichi Imai, Masahiro Nakagawa, Tsuyoshi Takahashi, Motoshi Ichikawa and Mineo Kurokawa
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1588

Zebrafish Stem/Progenitor Factor msi2b Exhibits Two Phases of Activity Mediated by Different Splice Variants (pages 558–571)
Tatiana Hochgreb-Hägele, Daniel E. S. Koo, Neha M. Das and Marianne E. Bronner
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1583

Metabolically Active Human Brown Adipose Tissue Derived Stem Cells (pages 572–581)
Francisco J Silva, Dolly J Holt, Vanessa Vargas, James Yockman, Sihem Boudina, Donald Atkinson, David W. Grainger, Monica P. Revelo, Warren Sherman, David A. Bull and Amit N. Patel
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1595

Exonuclease 1 is a Critical Mediator of Survival During DNA Double Strand Break Repair in Nonquiescent Hematopoietic Stem and Progenitor Cells (pages 582–593)
Amar Desai, Yulan Qing and Stanton L. Gerson
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1596

Embryonic Stem Cells/Induced Pluripotent Stem Cells

Brief Report: Astrogliosis Promotes Functional Recovery of Completely Transected Spinal Cord Following Transplantation of hESC-Derived Oligodendrocyte and Motoneuron Progenitors (pages 594–599)
Dunja Lukovic, Lourdes Valdés-Sanchez, Irene Sanchez-Vera, Victoria Moreno-Manzano, Miodrag Stojkovic, Shomi S. Bhattacharya and Slaven Erceg
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1562

Errata

Erratum: Constitutive activation of RANK disrupts mammary cell fate leading to tumorigenesis (page 600)
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1601

This article corrects:
Constitutive activation of RANK disrupts mammary cell fate leading to tumorigenesis
Vol. 31, Issue 9, 1954–1965, Article first published online: 4 OCT 2013

Erratam: Reversing bone loss by directing mesenchymal stem cells to bone (page 601)
Article first published online: 13 JAN 2014 | DOI: 10.1002/stem.1617

This article corrects:
Reversing bone loss by directing mesenchymal stem cells to bone
Vol. 31, Issue 9, 2003–2014, Article first published online: 4 OCT 2013