At the same time the team is testing an innovative new treatment regimen designed to prevent rejection of the limbs. During the transplant procedure Marrocco was given an infusion of the donor’s bone marrow cells.
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Coverage of the latest news and updates from the field of stem cells and regenerative medicine.
The study looked at the $1.5 billion in grant awards committed by July 2012, and the one-time economic impact they will have through 2014. These awards represent half of the $3 billion CIRM was allotted through the passage of Proposition 71 in 2004.
"We're finding that the effect of stem cell therapy is indirect. It stimulates proliferation of dormant surviving host heart tissue, and it attracts stem cells already in the heart.
"We're finding that the effect of stem cell therapy is indirect. It stimulates proliferation of dormant surviving host heart tissue, and it attracts stem cells already in the heart.
At the time of his death, Blume was recruiting patients for several clinical trials involving hematopoietic stem cells.
The new approach, not yet tested in patients, involves isolating cells from banked donor corneas to grow replacement corneal tissue in the lab. The advantage is that cells from a single donor could potentially benefit multiple patients with impaired vision.
The product, SB623, is being delivered to the damaged region of the brains of people who have suffered an ischemic stroke, which results from an obstruction within a blood vessel supplying blood to the brain. Ischemic strokes account for 87 percent of all stroke cases.
The work is important because networks of new blood vessels, assembled in the lab for transplanting into patients, could be a boon to those whose circulatory systems have been damaged by heart disease, diabetes and other illnesses.