DURHAM, N.C. JUNE 11, 2019 - A study released today in STEM CELLS demonstrates how extracellular vesicles derived from human mesenchymal stem cells (MSC-EV) are able to incorporate into human CD34+ cells, modifying their gene expression and increasing their viability and cloning ability. In a test on mice, MSC-EVs also increased the cells’ ability to lodge into bone marrow. This research performed by Prof. Sanchez-Guijo’s Lab at the IBSAL-University of Salamanca (Spain) could potentially overcome serious complications due to graft failure or poor engraftment from allogeneic stem cell transplantation.
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Press Releases from AlphaMed Press
DURHAM, N.C. (MAY 30, 2019) - A study released today in STEM CELLS Translational Medicine is the first to demonstrate an efficient delivery system for the sustained release of human placental stem cell (HPSC)-derived conditioned medium (CM) to treat acute kidney injuries. The platelet-rich plasma-based gel system was able to deliver CM into the injured kidney, where it helped restore function and regenerate injured tissue.
DURHAM, N.C. (MAY 14, 2019) - A study recently published in STEM CELLS shows a new method for accelerating human pluripotent stem cell-derived cardiomyocytes’ (hPSC-CMs) development. If a way can be found to overcome hPSC-CMs’ developmental immaturity, which leaves them functionally and structurally different from mature human cardiomyocytes, they can be powerful tools for disease modeling, drug development, basic research and new therapies. This study shows great promise in resolving this issue.
DURHAM, N.C. (APRIL 11, 2019) - A study released today in STEM CELLS shows how a new class of cancer drugs, called Smac mimetics, is effective in killing off the stem cells that lead to glioblastoma (GBM) depending on oxygen level. This might help pave the way to a new, more efficient method for treating the most common and aggressive form of brain cancer in adults.
DURHAM, N.C. (APRIL 09, 2019) - Stem cells collected from the patient’s own bone marrow holds great interest as a potential therapy for osteoarthritis of the knee (KOA) because of their ability to regenerate the damaged cartilage. The results were released today in STEM CELLS Translational Medicine (SCTM).
DURHAM, N.C. MARCH 26, 2019 - The potential for stem cells to reduce damage, regenerate tissue and promote functional recovery after a spinal cord injury (SCI) is being tested in several ongoing clinical trials. However, a new study released today in STEM CELLS Translational Medicine (SCTM) indicates that donor age-dependent stem cell therapy could help optimize cell treatment strategies for clinical translation.
Durham, NC – A groundbreaking study released today in STEM CELLS Translational Medicine shows that the gold standard for obtaining stem cells to use in transplantation therapy – harvesting them from the patient himself – is not the best way to go when attempting to regenerate bone in a person with type 1 diabetes.
Type 1 diabetes is linked to low bone density, which greatly increases the risk of fractures. Researchers don’t know exactly why — it might be that insulin, which is deficient in the disease, promotes bone growth and strength – but all agree that finding a way to address this issue is important.
DURHAM, N.C. FEBRUARY 04, 2019 - Benjamin “Beno” Freedman, Ph.D., is named STEM CELLS' Young Investigator of 2018 for his groundbreaking work with organoids in studying kidney structure and disease. This award fosters advancements in the fields of stem cells and regenerative medicine by honoring a young researcher who is principal author of an article published in STEM CELLS that is deemed to have the most impact and to push the boundaries of novel and insightful research.
Durham, NC - (January 28, 2019)– A study released today in STEM CELLS Translational Medicine provides a deeper and clearer understanding of how patients suffering vision loss in both eyes due to limbal stem cell deficiency (LSCD) might benefit from a stem cell transplant using donated cells. This is the first randomized, controlled study to investigate the safety and efficacy of this method, in which corneal epithelial stem cells procured from a deceased donor and expanded in the lab were transplanted in the patient’s eye.
DURHAM, N.C. JANUARY 23, 2019 - Yong-Beom Park, M.D., Ph.D., is named the STEM CELLS Translational Medicine’s Young Investigator of 2018 for his research in cartilage regeneration in osteoarthritic patients. The award fosters advancements in the field of stem cells and regenerative medicine by honoring a young researcher who is principle author of an article published in SCTM that is deemed to have the most impact and to push the boundaries of novel and insightful research.