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Positive Trial Results Supports Umbilical Cord Blood Therapy for the Treatment of Stroke

Trial results suggest that the intravenous infusion of UCB represents a non-invasive, safe, and feasible means to treat acute ischemic stroke

Origin and Adhesive Behavior of MSCs may Influence their Therapeutic Application

The site of origin of mesenchymal stem cells and their inherent adhesive capabilities may significantly influence their therapeutic application

What’s the Stem Cells Buzz this Week? - P2X7 and Adult Neurogenesis, Perivascular Stem Cell Precursors, Cellular Therapeutics and Clot Formation, and MSC-Based Drug Delivery Review!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

What Role do Inflammatory Cytokines Play in Creating T Cell Exhaustion in Cancer?

SHAHREKORD, (IR), August 2018 — A better understanding of the role secreted inflammatory cytokines play in the tumor microenvironment that results in the differentiation of effector T cells into exhausted T cells points to possible approaches to improve the antitumor activity of T cells and to intervene in T cell exhaustion.

New Research Opens Door to Expanding Stem Cells Available for Transplants

KANSAS CITY, MO (US), August 2018 —Researchers from the Stowers Institute for Medical Research and collaborators have identified a way to expand blood-forming, adult stem cells from human umbilical cord blood (hUCB). This development could make these cells available to more people, and be more readily accepted in those who undergo adult stem cell treatments for conditions such as leukemia, blood disorders, immune system diseases and other types of cancers, but who do not have an appropriate available bone marrow match.

Probe illuminates Elusive Cancer Stem Cells in Live Mice

CHAMPAIGN, IL (US), August 2018 — After a primary tumor is treated, cancer stem cells may still lurk in the body, ready to metastasize and cause a recurrence of the cancer in a form that’s more aggressive and resistant to treatment. University of Illinois researchers have developed a molecular probe that seeks out these elusive cells and lights them up so they can be identified, tracked and studied not only in cell cultures, but in their native environment: the body.

the AlDeSense marker makes the cancer stem cells light up with fluorescence.

Study Shows the Promise of Mesenchymal Stem Cells in Sepsis Therapy

What’s the Stem Cells Buzz this Week? - MSCs in Multiple Sclerosis, Unproven Stem Cell Interventions, ASCs in Endotoxemia, and Collagen-mediated Immune Dysfunction!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

New Stem Cell Model can be used to Test Treatments for Rare Nervous System Disorder

DUARTE, CA (US), August 2018 — A new stem cell model has been developed to assess possible treatments for a rare nervous system disorder that is in the same disease group as Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis (ALS). 

The finding moved researchers one step closer to finding a way to slow or treat Alzheimer’s disease and other neurodegenerative disorders. 

stem cell-derived astrocytes (green) inhibit the growth of precursor cells that become myelin and speed up the brain’s communication network

Stem Cell Research for Cystic Fibrosis Moves Forward

ADELAIDE, SA (AU), August 2018 — The fight against cystic fibrosis (CF) has taken a major step forward, with pioneering research by University of Adelaide scientists showing that cells causing the debilitating genetic disorder could be successfully replaced with healthy ones.

The research applies cell transplantation therapy, normally used in bone marrow transplants to treat immunodeficiency disorders.

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