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FoxM1 Regulates Muscle Stem Cell Proliferation and Survival via long non-coding RNAs

Muscle stem cell regulation by the FoxM1 transcription factor functions through the regulation of the Snhg8 and Gm26917 long non-coding RNAs

Stem Cell-derived Blastocysts Push Early Embryo Research Forward

The development of the “blastoid” via the combination of trophoblast and embryonic stem cells may prove an interesting model for the study of early development 

New Platform Poised to be Next Generation of Genetic Medicines

A City of Hope scientist has discovered a gene-editing technology that could efficiently and accurately correct the genetic defects that underlie certain diseases.

"Our editing platform provides a new tool for the precise correction of genetic mutations in this rapidly growing field," said Saswati Chatterjee, Ph.D., professor in the Department of Surgery. "Think of it as swapping out a mutated gene for a healthy gene to correct genetic mutations."

Study Shows how Stem Cell Injections Helped Dogs suffering from Osteoarthritis

Dr. Offer Zeira with dog.Durham, NC. - July 2018

Dr. Offer Zeira

Scientists Optimize Procedure Toward Regenerative Medicine for Bone Defects

Scientists from the New York Stem Cell Foundation (NYSCF) Research Institute have developed a new bone engineering technique called Segmental Additive Tissue Engineering (SATE). The technique, described in a paper published online in Scientific Reports, allows researchers to combine segments of bone engineered from stem cells to create large scale, personalized grafts that will enhance treatment for those suffering from bone disease or injury through regenerative medicine. 

New Findings on Coronary Artery Formation Could Change how Engineers try to Regrow Them

It’s tempting to think all it takes to regrow arteries lost to heart disease is encouraging the proliferation of new blood vessel cells, but that hasn’t worked out. Now, Stanford biologist Kristy Red-Horse, Ph.D., and colleagues think they’ve figured out part of the problem. As the researchers reported recently week in Nature, the process of turning a group of blood vessel cells into an artery actually requires that they stop growing, and trying to speed up their expansion may actually backfire.

What’s the Stem Cells Buzz this Week? - Astrocytic Gene Hydroxymethylation, Facilitating Cells, Megakaryocyte-induced Myeloproliferation, and a Regenerative Medicine Roadmap!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

Mesenchymal Stem Cell-based Combinatorial Treatment Shows Promise for Lung Repair

New research suggests that a combination of MSCs and ATRA treatment in the presence of p70S6k1 signaling can enhance lung repair in a mouse emphysema model

How Short-term Fasting Affects Intestinal Stem Cell Function during Aging

Researchers discover than short-term fasting induces intestinal regenerative effects via increases in fatty acid oxidation in intestinal stem cells

Motor Cortex Targeting Improves Treatment of ALS by Engineered Human Neural Progenitor Cells

Researchers establish that transplantation of growth factor-secreting human NPCs can delay paralysis and extend lifespan in a rat model of ALS

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