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Regenerative Medicine Gains from Researchers’ New Ability to Predict Cell Conversion Factors

LUXEMBOURG CITY, (LU)  July 2018 - A newly developed computational method makes it possible for researchers to accurately predict how one subpopulation of cells can be converted into another.

"The method has great potential for regenerative medicine when it comes to replacing cell subpopulations that have been lost in the course of disease, for example," said Antonio del Sol, Ph.D., head of the Computational Biology group of the Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg.

Slide image, Cells.

Researchers characterize “Mutational Burden” of Human Induced Pluripotent Stem Cells

SAN DIEGO, CA (US)  July 2018 - The therapeutic potential of human induced pluripotent stem cells (iPSCs), which are capable of becoming almost any type of cell in the human body, is well-recognized and broadly pursued, but their mutational burden has not yet been fully characterized.

Boosting Stem Cells With Growth Factor May Help in Treating Critical Limb Ischemia in Hemodialysis Patients

 

Dr. Takayasu Ohtake and Dr. Shuzo KobayashiDURHAM, N.C. JULY 2018

Dr. Takayasu Ohtake and Dr. Shuzo Kobayashi

FoxM1 Regulates Muscle Stem Cell Proliferation and Survival via long non-coding RNAs

Muscle stem cell regulation by the FoxM1 transcription factor functions through the regulation of the Snhg8 and Gm26917 long non-coding RNAs

Stem Cell-derived Blastocysts Push Early Embryo Research Forward

The development of the “blastoid” via the combination of trophoblast and embryonic stem cells may prove an interesting model for the study of early development 

New Platform Poised to be Next Generation of Genetic Medicines

A City of Hope scientist has discovered a gene-editing technology that could efficiently and accurately correct the genetic defects that underlie certain diseases.

"Our editing platform provides a new tool for the precise correction of genetic mutations in this rapidly growing field," said Saswati Chatterjee, Ph.D., professor in the Department of Surgery. "Think of it as swapping out a mutated gene for a healthy gene to correct genetic mutations."

Study Shows how Stem Cell Injections Helped Dogs suffering from Osteoarthritis

Dr. Offer Zeira with dog.Durham, NC. - July 2018

Dr. Offer Zeira

Scientists Optimize Procedure Toward Regenerative Medicine for Bone Defects

Scientists from the New York Stem Cell Foundation (NYSCF) Research Institute have developed a new bone engineering technique called Segmental Additive Tissue Engineering (SATE). The technique, described in a paper published online in Scientific Reports, allows researchers to combine segments of bone engineered from stem cells to create large scale, personalized grafts that will enhance treatment for those suffering from bone disease or injury through regenerative medicine. 

New Findings on Coronary Artery Formation Could Change how Engineers try to Regrow Them

It’s tempting to think all it takes to regrow arteries lost to heart disease is encouraging the proliferation of new blood vessel cells, but that hasn’t worked out. Now, Stanford biologist Kristy Red-Horse, Ph.D., and colleagues think they’ve figured out part of the problem. As the researchers reported recently week in Nature, the process of turning a group of blood vessel cells into an artery actually requires that they stop growing, and trying to speed up their expansion may actually backfire.

What’s the Stem Cells Buzz this Week? - Astrocytic Gene Hydroxymethylation, Facilitating Cells, Megakaryocyte-induced Myeloproliferation, and a Regenerative Medicine Roadmap!

The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond!

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