A recent STEM CELLS Translational Medicine study led by Lei Liu (Sichuan University, Chengdu, Sichuan, China) recently described a novel long noncoding (lnc)RNA (lncRNA‐Adi) highly expressed in adipogenic‐induced adipose-derived mesenchymal stem cells (ASCs).
The in vitro expansion of mesenchymal stem cells leads to a decrease in their proliferative and therapeutic capacity, making basic research on factors regulating proliferation of fundamental importance for their successful translation into clinical applications.
Bone regrowth may be achieved using different biomaterial scaffolds that provide structural and biological cues to stem cells to stimulate osteogenic differentiation. Furthermore, new knowledge regarding the mechanisms of bone repair is of paramount importance to address the significant steps required for precise translational medicine to treat patients.
The tissue stromal vascular fraction of adipose tissue, a heterogeneous cell population containing adipose‐derived stem cells, has been successfully applied in translational studies and clinical trials.
The Stem Cells Portal is a shared platform for the STEM CELLS and STEM CELLS Translational Medicine sister journals, providing up-to-the-minute coverage of the latest research from bench science and developments to clinical applications.