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Mesenchymal Stem Cells

Niche Notch Signaling Supports Dental MSC-like Perivascular Cell Function

Findings support for the pivotal importance of Notch signaling in the crosstalk between dental MSC-like perivascular cells and their niches in tissue homeostasis and regeneration 

MSC Therapy for AKI Treatment

A new study describes the application of an ex vivo drug delivery device containing immobilized of MSCs to the treatment of acute kidney injury

MSC-induced Antibacterial Defense Mechanisms

A new study using an equine model provides further support to the value of mesenchymal stem cell secretome-based treatments for infected wounds

MSC-EVs for Neurodegenerative Disease

A new review summarizes current research concerning intranasally-administered MSC-EVs administrated and their potential as a therapeutic approach

How MSCs Differentiate into iCAFs

ELF3 induces the differentiation of mesenchymal stem cells into carcinoma-associated fibroblasts exhibiting an inflammatory phenotype

Scalable Generation of iPSC-MSCs

This study represents the first description of a robust, scalable, and cost-effective method for generating immunomodulatory human iPSC-MSCs

Continued Efficacy and Safety of Stempeucel® for CLI

The safe and tolerable intramuscular administration of stempeucel may represent an effective alternative treatment in Buerger's disease patients

How MSC-EVs Influence Angiogenesis and Chondrogenesis

Researchers compare extracellular vesicles isolated from differing MSC types with regards to their ability to influence angiogenesis and chondrogenesis

Metabolically-engineered MSC-derived Exosomes – A New Treatment for Rheumatoid Arthritis

Metabolic glycoengineering of adipose-derived MSCs and enhanced isolation techniques generate exosomes that may represent a means of treating rheumatoid arthritis

The Abca4/miR-351-3p – The Key to Therapeutic Success in Amniotic Fluid MSCs?

Modulating the Abca4/miR-351-3p axis may generate amniotic fluid-derived mesenchymal stem cells suited to regenerative medicine applications 

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