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iPSCs - Quick Stepping Towards the Clinic?

A new strategy to create patient specific induced pluripotent stem cells brings these cells closer to application in the clinic.

Boosting ESC Differentiation: Choose Your Expansion Medium Wisely

Researchers find that altering human ESC expansion medium can alter subsequent differentiation potential in a reversible manner

Could NG2 Provide a Break Through for Spinal Cord Injury?

Nerve glial antigen 2 expressing neural cells-derived from ESCs may allow for delayed spinal cord regeneration through the penetration of the protective glial scar

Rebuilding a Broken Heart with ESC-derived Purkinje cells

For the first time, researchers have demonstrated the differentiation of specialized heart cells which help to keep the heart beating in a normal fashion

Understanding the Intricacies of ESC Signaling

Researchers investigating signaling pathways which control pluripotency highlight newly found interactions and redundancies in mouse embryonic stem cells

Dental Stem Cells: An Intriguing Treatment for Corneal Blindness?

Researchers show that stem cells extracted from teeth may be useful in the treatment of blindness.

How do we Test for Immunogenicity of Human iPSC-Derived Cells?

Researchers demonstrate that currently used systems assessments of human iPSC immunogenicity are not sufficient.

Creating Tolerance for Human Embryonic Stem Cell Graft Derivatives

Short term T-cell mediated immune response blockade promotes the functionality of hESC-derivative grafts in immune-competent mice.

Simple Substrates Aid Stem Cell Differentiation

Cheap and simple growth substrates are discovered to aid differentiation of stem cells as compared to more complex and expensive alternatives
ESC/iPSCs

Quick and Easy Recipe for Mature Neurons from iPSCs

A quick and easy differentiation protocol for neural stem cells and their derivatives from human induced pluripotent stem cells

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