Scientists link a common mutation in patients with neuropsychiatric disorders to deregulated neuronal synapses through generating patient-specific induced pluripotent stem cells and following their differentiation
Researchers find that neural stem cells, but not terminally differentiated neural cell types, differentiated from iPSCs can revert to a pluripotent like state and potentially problematic for use in transplants.
Using a non-human primate model, researchers demonstrate that sufficient numbers of human ESC-derived cardiomyocytes can be produced, stored, and transplanted, leading to good levels of engraftment and electrical coupling
A new study outlines the design and generation of a fluorescent induced pluripotent stem cell line for tracking cells post-differentiation after transplantation, describing problems and solutions along the way.
The Stem Cells Portal is a shared platform for the STEM CELLS and STEM CELLS Translational Medicine sister journals, providing up-to-the-minute coverage of the latest research from bench science and developments to clinical applications.